Exam 2 Nobel Winners Flashcards
Morgan
role of chromosome in heredity
Lewis
genetic control of early embryonic development (used forward screening)
Nusslein-Volhard
genetic control of early embryonic development (used forward screening)
Wieschaus
genetic control of early embryonic development (used forward screening)
Capecchi
creation of KO mice
Evans
creation of KO mice
Smithies
creation of KO mice
Tsien
discovery of GFP
Chalfie
discovery of GFP
Shimomura
discovery of GFP
Fire
mechanism of RNAi
Mello
mechanism of RNAi
Sherrington
described synapses
Loewi
chemical transmission of nerve impulses
Dale
chemical transmission of nerve impulses
Katz
synaptic function at frog NMJ
Rothman
vesicle transport in cells
Scheckman
vesicle transport in cells
Sudhof
vesicle transport in cells
You can use Poisson when
Probability of release is low, number of possible release sites is high
GCaMP
genetically encoded calcium indicator, made up of EGFP, Calmodulin, and M13
Thy1
widely expressed in neurons, so good to use to promote GCaMP to detect neuronal activity