Exam 1 Flashcards

1
Q

The clinic nurse develops a plan of care for a client w/emphysema who will be started on a long-term steroid therapy. Which specific instruction would the nurse include in the plan of care?

A

Instruct the client to return to the clinic for monitoring of blood glucose levels

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2
Q

A client w/ a severe allergic reaction is prescribed IV steroids. The RN would expect that which desired effect would be achieved?

A

⬇️Decreased inflammation

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3
Q

A client who had a cold is seen in the ER w/an inability to void. Because the client has a hx of BPH, the RN determines that the client would be questioned about the use of which Rx?

A

Decongestants

Urinary retention is triggered by decongestants

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4
Q

A client has an Rx to take Guifenesin. The RN determines that the client understands the proper administration of this Rx if the client states they will perform which action?

A

Take the tablet with a full glass of water

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5
Q

The RN is preparing to administer a dose of noloxone IV to a client w/an opioid overdose. Which supportive medical equipment would the RN plan to have at the clients bedside?

A

Resuscitation equipment

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6
Q

A client had begun therapy with theophylline. The nurse would teach the client to limit the intake of which items while taking this medication?

A

Coffee, cola, and chocolate

Theophylline is a bronchodilator & must limit xanthine containing foods

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7
Q

A client who experiences allergic rhinitis asks the RN about a nasal steroid. How would the nurse reply?

A

This medication works locally & decreases inflammation

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8
Q

The RN is administering a dose of albuterol to a client. The RN would monitor for which side effect of this med?

A

Increased pulse

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9
Q

The RN is caring for a client with COPD who is receiving theophylline. The RN monitors the serum theophylline level & concludes that the Rx dosage may need to be increased if which value is noted?

A

5mg/ml

The therapeutic serum range is 10-20mg/ml

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10
Q

A client has been given a Rx for benzonatate. Which observation would the RN look for to evaluate the effectiveness of the Rx?

A

Calming the clients persistent cough

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11
Q

A client has begun to use methylxanthine bronchodilator. What beverage would the nurse plan to teach the client to avoid while taking this Rx.

A

Coffee

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12
Q

A client is taking albuterol by inhalation cannot cough up secretions. What would the RN suggest that the client do to assist in expectoration of secretions

A

Drink increased amounts of fluids daily

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13
Q

A client w/a Rx to take theophylline daily has been given Rx instructions by the RN. What statement by the client indicates the need for further education regarding the Rx?

A

“I will take the daily dose at bedtime”

This Rx should be taken in the morning

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14
Q

Cromolyn sodium is prescribed for the client with allergic asthma. What goal does the RN expect to achieve by administration of this Rx?

A

Inhibition of the release of mediators from mast cells after exposure to an antigen

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15
Q

A client has an Rx to take guaifenesin. The Rn would conclude that the client understands the most effective use of this Tx if the client states the need to take which action?

A

Take the tablet with a full glass of water

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16
Q

The RN is preparing to administer albuterol to a client. Which parameters would the Rn assess before and during therapy?

A

Lung sounds and presence of dyspnea

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17
Q

A home care nurse has observed a client self-administer a dose of an Andrenergic bronchodilator via metered dose inhaler. Within a short time, the client begins to wheeze loudly. The RN understands that this is the result of which occurrence?

A

Paradoxical bronchospasm, which must be reported to the PCP

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18
Q

A client receiving the oral theophylline is due to have a level drawn. The RN would question the client to ensure that the client has not ingested which substance before the blood sample is drawn?

A

Coffee

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19
Q

The client questions the RN as to why the PCP switched the usual Rx from a metered dose inhaler to a dry powder inhaler. The RN would respond correctly by providing which facts?

A

Dry powdered inhalers pose no environmental risks
Dry powdered inhalers deliver more Rx to the lungs
Dry powdered inhalers require less hand-to-lung coordination

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20
Q

Which statement made by a client taking montelukast indicated the need for further teaching?

A

“I will take the medication when I first notice I am having trouble breathing”

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21
Q

When evaluating an asthmatic clients knowledge of self care, the RN recognizes that additional instruction is needed when the client states?

A

“ I use my corticosteroid inhaler each time I feel SOB”

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22
Q

The RN would monitor the client receiving the 1st dose of albuterol for which side or adverse effect of this Rx?

A

Tachycardia

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23
Q

The client has a prescription to receive pirbuterol 2 puffs & beclomethasone dipropionate 2 puffs by metered dose inhaler. The RN plans to give these medications in which way to ensure effectiveness?

A

Administering the pirbuterol before the beclomethasone

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24
Q

A client is taking Theophylline has a serum level of 15mcg/ml. How does the RN interpret the lab value?

A

In the middle of the therapeutic range.

The range is 10-20mcg/ml

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25
Q

The PCP prescribed cromolyn for the client w/asthma. The RN identifies that the client correctly understands the purpose of this med when the client states that the med will produce which effect t?

A

Suppresses an allergic response

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26
Q

The RN is teaching a client about the effectiveness of diphenhydramine, an ingredient in the cough suppressant prescribed for the client. The RN would plan to tell the client to take which measure while taking this med?

A

Avoid activities requiring mental alertness

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27
Q

A client has begun therapy with a xanthine bronchodilator. The RN determines that the client understands dietary alterations if the client states to limit which items while taking this med?

A

Coffee and chocolate

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28
Q

A cromolym sodium inhaler is prescribed for a client w/allergic asthma. The RN provides instructions regarding the adverse effects of this medication & would tell the client that which undesirable effect is associated with/this medication

A

Bronchospasm

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29
Q

Terbutaline is prescribed for a client with bronchitis. Which disorder in the clients medical history required caution by the nurse?

A

Diabetes millitus

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30
Q

The RN has a prescription to give you a client salmetrol, 2 puffs, & beclomethasone dipropionate, 2 puffs, by metered dose inhaler. The RN would administer the med using which procedure?

A

Salmetrol first then beclomethasone

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31
Q

A client begins therapy with/theophylline. The RN plans to reach the client to limit the intake of which items while taking this med?

A

Coffee, cola, and chocolate

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32
Q

The RN is dating for a client receiving an albuterol/ipratropium nebulized breathing treatment. Which report from the client would the RN note as expected side effect of this combo med?

A

“I feel as though my heart is racing”

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33
Q

What are Antineoplastic Drugs?

(Auntie-o-plastic)
👩🏻-o-plastic

A

💊 to treat CA
Narrow therapeutic 🪟
Myelosuppression

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34
Q

RBC value ♥️

A

4.5-6

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35
Q

WBC Value 🤍

A

5,000-10,000

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36
Q

Platelet 🍽️ Value

A

150-400

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37
Q

Absolute neutrophil count ✖️➕➗🟰

A

(% segs ➕% bands) ✖️ WBC✖️10

🟰ANC

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38
Q

Methotrexate

A

Folate antagonist
Lowers immune
Bright 💛 urine
Drug 🩸levels need to be drawn
🛟💊- leukovorin
Adverse- Pulmonary fibrosis 🫁

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39
Q

Cladribine is what class of drugs?

A

Purine antagonist

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40
Q

cytarabine 👀

(See-why-Tara-bee)
👓👀🤷🏽‍♀️💃🏼🐝

A

You C with your 👀- conjunctivitis 🦠
Pyrimidine antagonist
Cytarabine syndrome:
🤒, 💪🏽& 🦴 pain, rash, conjunctivitis
Pretreat w/ Benadryl, APAP, steroids
(APAP not NSAIDs)

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41
Q

capecitabine

(Cape-cite-a-bean)
🦸🏽‍♀️cite-a-🫘

A

For breast & colon CA
Pyrimidine antagonist
Adverse effects-
🚽D/N/V🤮, 👋🏼🦶🏼👄syndrome, painful erythema

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42
Q

fluorouracil

(Flu-or-a-seal)
🤒or a 🦭

A

Palliative tx for CA
Pyrimidine antagonist

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43
Q

gemcitabine

💎♦️💠

A

1st line for Pancreatic CA
Pyrimidine antagonist

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44
Q

etopside

topsie-turbie 😵‍💫

A

Mitotic inhibitor
Adverse effect:
⬇️ Significant Hypotension

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45
Q

paclitaxel

(pack-lit-ax-el)
🎒🔥🪓el

A

Mitotic inhibitor
Breast, ovarian. Kaposis Sarcoma
Poorly tolerated
Pre 💊- dexamethasone, diphenhydramine💗, antacids
(Dark rash)

46
Q

vincristine

👩🏻🦶🏼

A

Never intrathecal, spine will 💀
Adverse effects:
Constipation 🚽-senna 💊
Peripheral neuropathy 📌
🦶🏼drop- notify Dr change 💊

47
Q

tOpOtecan

A

topoisomerase inhibitor (only)
Metastatic ovarian CA & 🫁 CA

Wait ⏳24hrs from chemo to give GCSF 💊

48
Q

L- asparaginase

A

antineoplastic enzymes
Made from ecoli 💩
Allergic reaction is common 🥵
Cor cart close ⚕️
Adverse affects:
N/V 🤮, 🫃🏻abd pain
Pancreatitis- notify Dr
⏳prolonged clotting 🩸times

49
Q

Erwinia asparaginase

A

antineoplastic enzymes
made w/ erwina vs ecoli so less reaction
Expensive 🤑

50
Q

Chemotherapy administration 💊

A

Central line 🩸
(Peripheral can cause necrosis)
Chemo approved 🧤
Stay in room for 15 min ⏰

51
Q

Medication to stop vesicant reaction

A

hyaluronidase 💊

🧊cold compress

52
Q

Tumor Lysis Syndrome

A

Cell breaks open:
⬆️uric acid- shuts down kidneys
⬆️ phosphate- shuts down kidneys
⬆️ potassium (ekg)
⬇️ calcium
Symptoms:
flank pain, 🤮, oliguria
Tetany 🤌🏽
Cardiac dysrhythmia
Seizures 🫨, ☠️

53
Q

Alktlating Drugs saying

A

-B- nice to your lungs and
-D- heart and
-C- your kidneys and bladder not bleed

54
Q

What are the three types of Alkylating drugs? 💊

A

Classic 🎼 alkylstors
Nitrosureas 🏎️💨
Miscellaneous alkylators 🤷🏽‍♀️

55
Q

mechlorethamine

(Mikalo 🧑🏼💨)

A

(Nitrogen Mustard)
Used to be gas
Blisters 💦 and get 🦠

56
Q

cyclophosphamide

A

Classic alkylator 💊
Adverse effects:
Hemorrhagic cystitis( Inflam> to🩸)
IVF hydrated 💧(⬇️ chemo in bladder)
Mesna💊- protects bladder

💧infuse before & after 💊
At least 2 liters
Needs to pee 💛 q 2-3 hours

“C your kidneys and bladder not 🩸”

57
Q

ifosfamide

A

Classic alkylator 🎼
Adverse effects:
Hemorrhagic cystitis(Inflam > to 🩸)
IVF Hydrated- 💧dilute 💊 in bladder
Mesna💊- protects bladder

At least 2 L of 💧
💛pee q 2-3 hours
“ C your kidneys & bladder not 🩸)

58
Q

cisplatin 💚🍌 (Plantain)

A

Miscellaneous alkylator🤷🏽‍♀️
Adverse effects:
Nephrotoxicity
2,000-3,000 IVF 💧/ during
Peripheral neuropathy 📌
Ototoxicity- test 👂🏼frequently

“C your kidneys & bladder not 🩸”

59
Q

carboplantin

(Carb-plantain)
🍝💚🍌

A

Miscellaneous alkylator🤷🏽‍♀️
Adverse effects:
Severe 🦴marrow suppression
Nephrotoxicity
2,000-3,000 💧IVF during tx

“C you bladder & kidneys not 🩸”

60
Q

busulfan

(Bus of fan)
🚏🚌 of 🪭

A

Miscellaneous alkylator🤷🏽‍♀️

Adverse effect:
Pulmonary fibrosis🩻- 🫁get infiltrate
Hyperuricemia- ⬆️uric acid needs allopurinol 💊

“B nice to your lungs”

61
Q

Cytotoxic Antibiotics 💊

A

Too toxic 💀 to treat infections 🦠
Lifetime maximum 🛑🫷
🦴 marrow suppression
2types:
Anthracyclines & other cytotoxic Abx

62
Q

doxrubicin

(Dox- ruby- cin)
💎♦️

A

Anthracycline 🚴‍♀️
EKG, Echo
L- ventricular🫀 ejection ➗
Adverse side effects:
🫀💀cardiotoxic
🫀Heart Failure
🫃🏻weight gain- daily ⚖️
🫁sounds- crackles

“D heart”

63
Q

daunorubicin

(Dawn dish soap- ruby-cin)
🧼🧴♦️💎

A

Anthracycline 🚴‍♀️
🧡/❤️ urine
Adverse effects:
🫀💀cardiotoxic
🫀⬇️ heart failure
🫃🏻weight gain- daily ⚖️
🫁👂🏼- crackles

ECHO/EKG “D heart”

64
Q

bleomycin

(Ble-my-son)
🐝👆🏼👦🏻

A

Other cytotoxic antibiotics
Adverse effects:
Pneumonitis 🫁
Pulmonary fibrosis
- PFT & CXR 🩻

“B nice to your lungs”

65
Q

bevacizumab

(Beverly (Bev)- scissor-mob)
💃🏼a✂️🇮🇹mob

A

Miscellaneous Antineoplastic 🚂🪀
Angiogenesis inhibitor
(🛑new 🩸🪢to tumor)
▪️warning❗️-
🙅🏼‍♂️28 ☀️before surgery 🔪
Wound dehiscence 🥓
⬇️ wound healing ❤️‍🩹
Adverse:
HTN, Hypotension

66
Q

hydroxyurea

(Hydro-xy-uria)
💦xy💛

A

Miscellaneous Antineoplastic 🚂🪀
Sickle cell disease
In conjunction with/ radiation ☢️

67
Q

Hormonal Drugs

A

Can be
Estrogen ➕or progesterone➕
🛑✋🏽growth
Contraindicated in
DVT🩸, clotting disorders

68
Q

tamofixen

(Tammy is fixin )
💃🏼🛠️

A

Treats & prevents breast CA

Adverse effects:
Hypercalcemia⬆️🍊
(constipation, kidneys, flank pain)
“Tammy💃🏼 is fixin 🛠️to go to the bathroom 🚽 💩“
Hypolipidemia- lowers LDL 🙌🏽

69
Q

megestrol (Megace) 🦈

(Strong shark)

A

Suppresses luteinizing hormone
Adverse effects:
DVT 🪢🩸
Weight gain🫃🏻- good for people w/ HIV or geriatric 👵🏽👴🏼

70
Q

Immunosuppressant drugs⬇️🧗‍♀️

A

For immune disorders
Organ transplant
⬇️ T-lymphocyte
Risk for 🦠 or CA
Metabolized by p450 enzymes
(Lowers immune so body doesn’t attack or reject organs)

71
Q

cyclosporine 🚴‍♀️🚵‍♀️

A

Immunosuppressant drugs⬇️🧗‍♀️
Narrow therapeutic 🪟
Tastes gross 🤮 🧃
🚫styrofoam🥤- attaches med & breaks down
🚫grapefruit- changes☠️metabolism

▪️warning ❗️
☠️🦠 (🤒 is an emergency)
Nephrotoxicity 🫘
Hepatotixicity
Encephalopathy 🧠
Skin CA

Adverse effects:
Infx, 👄💭gum hyperplasia, ⬆️hair growth🧔🏼‍♀️, HTN

72
Q

tacrolimus

(Tac-ro-lime-us)
📌ro🍋‍🟩🇺🇸

A

Immunosuppressant drugs⬇️🧗‍♀️
x💯potent than cyclosporine
🚫🥤- attaches to med
🚫grapefruit ☠️

▪️warning❗️
Malignancy, ☠️🦠infections

Adverse effects:
Diarrhea 🧻, HTN, ⬆️hyperglycem💉

73
Q

sirolimus

(siren- lime-us)
🚨🍋‍🟩🇺🇸

A

Immunosuppressant drugs⬇️🧗‍♀️
Not as ☠️ as tacrolimus
🚫🥤
🚫grapefruit
▪️warning❗️
Malignancies, ☠️🦠
Adverse side effects:
🧻diarrhea, HTN, hyperglycemia 💉

74
Q

mycophenolate mofetil

“My mocos are late- muffins”
🤧🦠- 🧁

A

Immunosuppressant drugs⬇️🧗‍♀️
Intercept cells 🏈
HTN

▪️warning❗️
Congenital malformations 🧟
Spontaneous abortion 😢

75
Q

Nursing implications for Immunosuppressant drugs⬇️🧗‍♀️

A

Taken for life ☀️- take with 🧃
👀Watch for 🦠
Birth control attacks 👶🏽
🚫💉vaccinations

76
Q

What is erythropoiesis?

A

Lower RBC 🩸
Normal RBC value is 4.5-6
Norma Reticulocyte is. 0.5-2%

Reticulocytes are just babies 👶🏽

77
Q

What are ESAs?

A

Eythoropoiesis- stimulating Anents

Treatment of:
End stage kidney 🫘disease
Chemo induced anemia
Zidovudine induced anemia

Side effect- 🦴pain 😖

78
Q

epoetin Alfa

(💪🏽)

A

Synthetic form of hormone erythropoietin

Takes 2-3wks for effects

darbepoetin (alternative)- long acting

79
Q

Nursing implications for ESAs

A

Significant HTN ⬆️
🚫if Hgb is low:
>10 w/out renal disease
>11 w/renal🫘 disease

🚫shake 💊
Keep 🧊
Sub q injection

80
Q

Leukopenia Drug

A

Given before pt has an 🦠, but not W/in 24 hrs of Chemo

Goal of WBC >10,000

Adverse effects:
🦴pain, ruptured spleen
(no sports 🏈 )

81
Q

filgrastim

A

Leukopenia drug

Stimulates granulocytes G-CSF

(granulocyte colony stimulating factor)

82
Q

pegfilgrastim

In commercial ❗️

A

Leukopenia drug

Lasts longer that filgrastim,
reduces number of injections 💉

83
Q

sargeamostim

A

Leukopenia drug

Stimulsted granulocytes & macrophages

GM-CSF

84
Q

Thrombocytopenia Drugs

A

oprelvekin- for 🩸disorders & CA
(⬇️# of platelet transfusions)

romiplostim- for idiopathic thrombocytopenia purpura (ITP)

85
Q

Interferon Drugs

A

Antiviral, Antitumor, and Immunomodulating

Adverse effects: flu like sx, fatigue, 🤒, hypotension, GI issues, liver issues, seizure🫨, depression

Pre💊- APAP & Benadryl (fever & itch)

86
Q

Interferon Classes

A

Alpha💪🏽- for CA, Hep C, Kaposi’s sarcoma

Beta🐠- for MS

Gamma👵🏽- osteoporosis

87
Q

Monoclonal Antibodies

A

CA, RA, MS, organ transplant
🎯CA cells
Suffix-mab

▪️warning❗️:
Risk for lymphomas & other CA
🫀failure

Contraindicated:
TB, active 🦠

Adverse effects:
🤒, dyspnea, chills 🥶

88
Q

adalimumab

In commercial ❗️

A

Monoclonal Antibodies

For RA, psoriatic arthritis, Crohn’s disease

89
Q

belimumab

A

Monoclonal Antibodies

For lupus

90
Q

bevacizumab

A

Monoclonal Antibodies

Colon/rectal CA, liver, glioblastoma

91
Q

infliximab (Remicade)

A

Monoclonal Antibodies
Very common 💊

For RA, Crohn’s disease, ulcerative colitis

92
Q

rituximab

A

Monoclonal Antibodies

Non-Hodgkin lymphoma

93
Q

trastuzumab

A

Monoclonal Antibodies

For breast CA

▪️warning❗️-cardiomyopathy

94
Q

Interleukin Drugs

A

Contraindicated in:
TB, active 🦠

Adverse effect:
Capillary leak syndrome
(☠️, 🚫perfusion, leads to hypotension)

95
Q

aldesleukin

A

Interleukin 💊

For Melanoma, HIV, and AIDs

96
Q

secukinumab

In commercial ❗️

A

Interleukin 💊

for plaque psoriasis, psoriatic arthritis, ankylosing spondylitis

97
Q

Disease modifying antirheumatic drugs

DMARD

A

Treat w/
NSAIDS & corticosteroids 💊

Properties:
Anti inflammatory 💭
Antiarthritic
Immunomodulating

Contraindicated:
TB, active infx 🦠

98
Q

etanercept

(e-tan-intercept)
☀️👙🏈

A

Showed on commercial❗️

Antirheumatic 💊
Better shelf life due to latex
Watch for latex allergy⚠️

99
Q

methotrexate

A

Yellow pill 💊

Use with leukovorin 💊 for methotrexate toxicity

100
Q

Screen & treat for this disease prior to start of biological response modifying drugs

A

Tuberculosis 🦠

101
Q

Adverse effect of leukopenia 💊

A

🦴pain

102
Q

Lymphoma from monoclonal antibodies

A

▪️warning ❗️

103
Q

Gamma 👵🏽 interferon is used to treat this disease

A

Osteoperosis 🦴

104
Q

Potentially ☠️effect of interlukins

A

Capillary leak 🚰syndrome

105
Q

Beta 🐠 interferon is used to treat those diseases

A

Multiple sclerosis

106
Q

Stimulates megakaryocytes to produce thrombocytes

A

Oprelvekin

107
Q

Mab ending

A

Monoclonal antibodies

108
Q

Goal is to ⬆️ WBCs

A

Leukopenia drugs

109
Q

Anti-inflammatory, immunodilatong, & antiarthritic properties

A

DMARD properties

110
Q

Important to premeditate w/benadryl and APAP

A

Interferon drugs 💊

111
Q

Be careful giving when giving etanercept

A

Latex