Exam 1

Question 1

Intracellular receptors

Answer 1

Have steroid, hormones, and structural relatives

Question 2

Steroid, hormones, and structural relatives

Answer 2

– Consist of cholesterol, testosterone, estradiol, cortisol, vitamin D, retinol acid
– Hormones go through p.m.
– Binds to receptor protein inside of plasm
– Receptor enters, nucleus, function, transcription factor
Receptor binding DNA to regulate expression

Question 3

Nitric oxide

Answer 3

– Nitric oxide released from cell
– Goes through plasma membrane into another cell
– Find receptor protein, cytoplasm, receptor
– guanylyl cyclase
– Signal binds, and enzymes are active

Question 4

What is nitroglycerin?

Answer 4

A drug to help relaxation during heart attacks it increases your nitric oxide

Question 5

What is Viagra?

Answer 5

Viagra make sure you maintain the level of cyclic GMP

Question 6

What are neurotransmitters

Answer 6

Nerve cells like peregrine. Consist of adrenaline dopamine serotonin, and a morphine, small and hydrophilic typically binds to a lion gated. I am on channel or to a receptor called G protein cup receptor.

Question 7

What are proteins in poly peptides?

Answer 7

They Varian size and typically are hydrophilic their growth factor proteins, and cytokines

Question 8

What are Eicosanoids

Answer 8

Hydrophobic lipids, too big to pass through the plasma membrane. They control blood vessel, dilation, and construction inflammation also.

Question 9

What is the procedure for ligand gated on channels?

Answer 9

– Ion gated channels start off, closed
– A lines to the outside of the channel, causing it to open
– When it opens ions go through into the cytoplasm of the cell

Question 10

What is the procedure for G protein coupled receptor?

Answer 10

– A signal binds to the terminal of the cell
– See terminal changes confirmation
– GDP is removed by using GEF and replaced with GPTP on Alpha
Alpha GTP is active and removed from beta and gamma
– Beta and gamma are active as well and downstream effects

Question 11

How do you enact or turn off a G protein cup receptor?

Answer 11

You’re remove the phosphate and it will replace GTP with GDP again

Question 12

Process of RTK dimerization auto phosphorylation

Answer 12

– Extra cellular is the receptor, while intracellular is the enzyme
– Start with signal, dimer growth, factor
– You get ligand induced receptor, dimerization
– Kindness domain is active and will fast forward tire, roasted of other receptors– Chinese domain is active and phosphate tyrosines of other receptors
-you will get auto or cross for elation which will increase activity