Eurkaryotic Cell Cycle Flashcards
1
Q
The enzymes and proteins necessary for cell division are
synthesized in which phase
A
G2
2
Q
A mutation in Cyclin E that interferes with its binding
to Cdk2 would prevent which of the following
processes?
A
Passage from G1 to S
3
Q
The DNA checkpoint kinases, Chk1 and Chk2, phosphorylate Cdc25
resulting in its inhibition. Cdc25 is required for the activation of
both Cdk1 and Cdk2. Inhibition of Cdk1 would lead to?
A
G2 phase arrest
4
Q
What effect would a mutant of Rb that can no longer be phosphorylated by
Cdk4/Cdk6 have on progression through the cell cycle?
A
Transcription of genes necessary for cell cycle progression would be
repressed
5
Q
Growth factors induce the synthesis of
A
Cyclin D