Erythropoisis Flashcards

1
Q

Erythropoises Stages

A

Mesoblastic
Hepatic
Medullary

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2
Q

Mesoblastic Stage

A

Mesoderm of yolk sac

Intravascular erth

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3
Q

Hepatic

A

5th week- liver, spleen

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4
Q

Medullary

A

5 month - bones

Extramedullary aftetbirth is abnormal

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5
Q

Erythpoi Stages

A
Stem cell
Progenitor
Precursor
Mature.      Baso- polychrom- acido
                    Reduc in RNA
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6
Q

Stem cell

A

Plurri and commited- myleoid. Lymphoid

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7
Q

Progenitor

A

BFR-E. Blast—

CFU-E colony—blast

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8
Q

Precursor

A

Blast- id in marow

Normobast. Pro, early, interm,late

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9
Q

Pronormoblast

A
Many nucleoi
Nucleus promi
No Hb
Baso- rna, polyribo, protein
Large, oval
Mitosis 
Less cyto
15-20 um
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10
Q

Early Normo

A
1st erythroblast
12-18
Baso erthblast...blue
Hetero-violet, euchro-pink...wheel spokes
Mitosis
Hb appears
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11
Q

Intermediate normo

A
10-15
Cyto- blue to pink..polychromatic
Nucleus reduced
No nuclie
More Hb- acido
Less mitosis
Heterochro clump-chekerboard
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12
Q

Late normo

A
7-12
No mitosis
Eosnophilic - orthochromatic ertblst
Pyktonic - cartwheel- nucleus degenrt
Hb complete
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