Epistasis Flashcards
20.4
Epistasis definition
Describes an interaction between genes at different loci (affecting a single phenotypic trait)
-genes may work antagonistically or in a complementary fashion
A gene is said to be epistatic when…
its presence modifies or suppresses the effect of a gene at another locus (the hypostatic gene)
Sometimes referred to as…
‘modifying’ or inhibiting’ genes
They can be
Dominant or recessive
Recessive epistasis
The presence of homozygous recessive alleles at the first locus prevents the expression of another allele at a second locus
Dominant epistasis
A dominant allele at the epistatic gene ‘masks’ the hypostatic gene (even if there is a dominant allele present at the hypostatic gene locus)
The presence of a dominant allele at the first locus prevents the expression of another allele at a second locus