Epilepsy Pharmacology

Question 1

Which anti seizure drugs are sodium channel blockers?

Answer 1

Lamotrigine
Carbamazepine
Phenytoin
Sodium valproate

Question 2

How else does sodium valproate work (other than by sodium channel inhibition)?

Answer 2

Increases GABA concentration

Question 3

What may Ethosuximide be useful for (although it is not first line)?

Answer 3

absent seizures

Question 4

Which medication is highly teratogenic?

Answer 4

sodium valproate

Question 5

First line for partial seizures?

Answer 5

Carbamazepine

Question 6

First line for generalized and absence seizures?

Answer 6

sodium valproate

Question 7

Second line for generalized seizures?

Answer 7

lamotrigine

Question 8

When should drug therapy be started?

Answer 8

after a minimum of 2 fits

Question 9

How many drugs should be used at a time?

Answer 9

only one at a time

Question 10

Which drug may cause gum hypertrophy?

Answer 10

phenytoin

Question 11

Which drug may cause a skin rash?

Answer 11

carbamazepine

Question 12

How does ethosuximide work?

Answer 12

Calcium channel inhibitor