Enzyme Inhibition

Question 1

What is an inhibitor?

Answer 1

A substance that decreases the rate of an enzyme controlled reaction and stopping it

Question 2

What are the two types of inhibitors?

Answer 2

• Competitive
• Non-Competitive

Question 3

What does a competitive inhibitor do?

Answer 3

It attached itself to an active site so that it occupies it and no ES complexes can be formed

Question 4

What does a non-competitive inhibitor do?

Answer 4

It attaches itself to an alternate site of the enzyme, altering the tertiary structure and thus the active site so it is no longer complimentary

Question 5

What is an allosteric region?

Answer 5

An alternate region of an enzyme where non-competitive inhibitors bind too

Question 6

What happens to the rate after increasing the substrate concentration, with a non-competitive inhibitor?

Answer 6

Thr effect of the inhibitor cannot be overcome by increasing the substrate concentration

Question 7

What happens to the rate after increasing the substrate concentration, with a competitive inhibitor?

Answer 7

The substrates overcome the inhibitors and the rate can achieve maximum