Enols and Enolates

Question 1

Show the enolate that will result from the deprotonation of the most acidic proton in each of the following species:

Answer 1

Question 2

curved arrow mechanism:

Answer 2

Question 3

Provide a curved-­arrow mechanism for the following reaction:

Answer 3

Question 4

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Question 5

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Question 6

Show the starting materials that would produce each of the following products via an aldol reaction:

Answer 6

Question 7

• Show the starting materials that would produce each of the following products via an aldol reaction:

Answer 7

Question 8

• Show the starting materials that would produce each of the following products via an aldol reaction:

Answer 8

Question 9

• Show the starting materials that would produce each of the following products via an aldol reaction:

Answer 9

Question 10

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Question 11

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Question 12

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Question 13

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Question 14

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Question 15

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Question 16

What is a Michael Reaction?

Answer 16

A Michael Reaction is a 1,4-­‐Addition of Enolates to Enones

Question 17

How can you recognize the Michael reaction?

Answer 17

Question 18

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Question 19

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Question 20

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Question 21

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Question 22

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Question 23

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Question 24

What is the structural motif found in products of Claisen condensations?

Answer 24

1,3 - dicarbonyl. Does not work in acid.