Embryo and fetal development and physiology Flashcards

1
Q

What form is the embryo in during implantation?

A

blastocyst

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2
Q

Where do male gonads develop from?

A

Wolffian ducts

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3
Q

Where do female gonads develop from?

A

Mullerian ducts

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4
Q

How many layers separate the maternal and fetal circulations?

A

3

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5
Q

What create a high surface area/volume ratio in the placenta?

A

fetal villi, suspended in intervillous spaces bathed with maternal blood

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6
Q

Transfer of O2 and CO2 occurs by what mechanism?

A

passive diffusion

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7
Q

Transfer of iron/vit C occurs by what?

A

active transport

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8
Q

Transfer of glucose and immunoglobulins occurs how?

A

facilitated diffusion

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9
Q

Is there a large or small placental reserve?

A

large - can afford to lose up to 30/40% of placental villi without evidence of placental insuffiency

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10
Q

What does the embryo consist almost entirely of?

A

water

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11
Q

When does a fetus become entirely dependent on its mother for nutrients?

A

10 weeks

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12
Q

When does heart start beating?

A

4/5 weeks

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13
Q

Chest movements are detected when?

A

11 weeks

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14
Q

What prevents alveolar collapse after birth?

A

surfactant

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15
Q

What makes surfactant?

A

type 2 pneumocytes

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16
Q

What promotes surfactant production, decreasing risk of RDS by 50%?

A

antenatal corticosteroid therapy

17
Q

What in breast milk helps protect against enteric infections?

A

IgA

18
Q

What is hCG most closely related to?

A

LH (shares subunit)

19
Q

When can hCG, produced by synctiotrophoblasts, be detected in the blood?

A

8-9 days post conception

20
Q

What maintains progesterone production from the corpus luteum until the placenta takes over at 6/8weeks

A

hCG

21
Q

What is the major source of progesterone AND oestrogen during pregnancy?

A

placenta