ECLAMPSIA IN DOGS Flashcards
Synonyms of eclampsia in dogs
- Lactation tetany
- Puerperal tetany
- Postpartum hypocalcemia
In dogs
Period in which eclampsia occur in dogs and which type of breeds
- Peak lactation 3-4weeks of whelping
- Small breeds with large litter
Also seen in large breeds and small lietters and in late gestation
Predisposing factors of eclampsia in dogs
- Inadequate perinatal nutrition
- Heavy lactation demand
- Improper Ca supplimentation
Pathophysiology of eclampsia in dogs
Excess calcium supplimentation during prenatal period—PTgland atrophy—PTH decrease—Ca homeostsis affected—decrease intestinal absorption and bone resorption—ECF Ca decrease—excitation threshold decreases—tetanic seizures—low threshold activation of Na channels—discharge repetitively without provocation—labour and dystocia causes tachypnoea and in turn leads to metabolic alkalosis and serum calcium binds to protein leading to further calcium depletion—hypoglycemia
CS of eclampsia in dogs
- Ataxia
- Hyperthermia
- Facial pruritis
- Tachycardia
- Salivation
- Irritability
- Poor maternal behaviour
- Restlessness
- Come
- Hypersensitivity
- death
* Tonic and clonic convulsions: SEIZURES
DD in eclampsia in dos
Idiopathic epilepsy
Meningioencephalitis
Toxicity
Hypoglycaemia
Mastitis
Metritis
Treatment for eclampsia in dogs
- 10% Ca gluconate@0.5-1.5ml/kg, over 10-30 min, once stable, dilute with equal amount of NS , S/C
- Avoid nursing of puppies for next 12-24hr
- After acute crisis, 25-50mg/kg/day in divided doses throughout lactation
- Corticosteroids- contraindicated
- High quality, nutritionally balanced diet
- Manage hyperthermia, hypoglycemia
- 500mg 200mg CaCO3 tab, Ca tablets avilable and dose 10-30mg/kg
- Milk replacer for puppies
Why is corticosteroid contraindicated?
Because it causes calciuria, decreased Ca
absorption and impairs osteoclasia.