E5 Infxn in immunocomp

Question 1

ANC value we consider to be neutropenia (risk factor for infection)

Answer 1

ANC <1000 cells/mm3

Question 2

ANC formula

Answer 2

WBC x (%polys+%bands)

Question 3

3 highlighted common bacterial pathogens

Answer 3

• staph aureus
• enterobacterales
• pseudomonas

Question 4

3 common fungi pathogens

Answer 4

candida spp
aspergillus
zygomycetes

Question 5

3 common viruses

Answer 5

HSV
VZV
CMV

Question 6

Cell-mediated immunity:
A. T-lymphocytes
B. B-lymphocytes

Answer 6

A

Question 7

Primary defense against intracellular pathogens.
A. cell-mediated immunity
B. humoral immunity

Answer 7

A

Question 8

Humoral immunity:
Primary defense against ___________ pathogens

Answer 8

extracellular

Question 9

2 things that reduce ability of host to defend against INTRAcellular pathogens

Answer 9

• underlying disease
• immunosuppressive drugs

Question 10

2 things that reduce ability of host to defend against EXTRAcellular pathogens

Answer 10

• underlying disease
• immunosuppressive drugs

Question 11

3 common pathogens in skin

Answer 11

• staph aureus
• staph epidermidis
• candida

Question 12

5 common pathogens that cause alteration of flora

Answer 12

• enterobacterales
• pseudomonas
• staph aureus
• candida
• aspergillus

Question 13

aspergillus spp:
Heme and HSCT pts -> prolonged ________

Answer 13

neutropenia

Question 14

what is the DoC for prophylaxis in protozoan infections?

Answer 14

TMP/SMX

Question 15

most important and often only clinical finding for presentation + diagnosis

Answer 15

fever

Question 16

3 labs used for diagnosis

Answer 16

• blood cultures
• CBC
• BMP or CMP

Question 17

2 diagnostic tools used

Answer 17

• imaging
• aspiration or biopsy

Question 18

management of febrile neutropenia:
empiric tx regimen should include anti__________ coverage

Answer 18

pseudomonal