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First Aid Pharm > Drugs: Cardio > Flashcards

Drugs: Cardio Flashcards

1
Q

Digoxin Use

A

HF, a. fib

inc contractility, dec conduction @ AV node and depress SA node

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2
Q

Ezetimibe AE

A

diarr, inc Liver function Test

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3
Q

Procainamide MOA

A

class IA Antiarryth

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4
Q

Fibrates AE

A

myopathy (inc risk with statins)

cholesterol gallstones

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5
Q

Digoxin MOA

A
  1. inhibit Na/K ATPase to inhibit Na/Ca exhanger causing inc IC Ca and inc ionotropy
  2. stim vagus nerve to dec HR
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6
Q

Nitrate Use

A

angina, acute coronary syndrome, pulm edema

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7
Q

BB OD tx

A

saline, atropine, glucagon

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8
Q

Nitrate AE

A

reflex tach (prevent w BB), hypotension, flushing, “Monday disease”

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9
Q

Class 1A Arryth use

A

atrial and ventricular arryth

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10
Q

Tx unstable angina and NSTEMI

A

Anticoag (Heparin), antiplatelet (ASA), BB, ACEi, statin

Sx control= morphine and nitroglycerin

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11
Q

Prinzmetal angina tx

A

CB, nitrate, smoking cessation

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12
Q

Digoxin AE

A

cholinergic, blurry yellow vision, arty, AV block, hyperK

renal fail and hypoK predispose to toxicity

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13
Q

1- HTN tx

A

thiazide diuretic, ACEi, ARBs, dihydropyridine CCB

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14
Q

Adenosine AE

A

flushing, hypotension, chest pain, doom, bronchospasm

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15
Q

Adenosine DDI

A

theophylline and caffeine (adenosine R antagonist)

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16
Q

Adenosine MOA

A

inc K efflux (hyperpolarize) and dec Ca current

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17
Q

Adenosine use

A

DOC to dx SVT

very short acting (15 sec)

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18
Q

Amiodarone is

A

class 3 antiarryth (K channel blocker)

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19
Q

Amio AE

A

pulm fibrosis, hepatotoxicity, hypo/hyperthyroid (40% iodine), CV (brady, heart block, HF), acts as happen (blue-grey skin deposits causing photodermititis, corneal deposits)

remember to check PFT, LFT, TFT

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20
Q

Amlodipine is

A

dihydropyridine CCB

works on vast Smooth muscle

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21
Q

Bezafibrate is

A

fibrate

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22
Q

Bile acid resin AE

A

GI upset, dec abs of drugs/vit ADEK

taste bad, gallstones

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23
Q

bile acid resin MOA

A

prevent intestinal reads of BA so liver must use cholesterol to make BA

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24
Q

Bile acid resin use

A

dec LDL, C diff

slightly inc HDL, slightly inc TAGs

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25
Buerger disease tx
smoking cessation
26
CCB AE
gingival hyperplasia, constipation, edema, CV depression, AV block, flushing, dizziness
27
CCB MOA
block voltage dependent L type Ca channels of cardiac and smooth muscle to dec contractility
28
cholestyramine is
bile acid resin
29
Class 1 antiarryth MOA
dec slope of phase 0
30
Class 1 antiarryth
Na channel blockers
31
Class 1B antiarryth use
post MI ventricular arryth, digitalis induced arryth
32
Class 1C antiarryth AE
proarryth (contra in structural/ischemic heart disease)
33
Class 1C antiarryth use
SVTs (only as last resort)
34
Class 2 antiarryth MOA
dec slope of phase 4
35
Class 2 antiarryth
BB
36
Class 2 antiarryth use
SVT, rate control in a. fib and a. flutter
37
class 3 antiarryth MOA
inc length of phase 3 (repolarization)
38
class 3 antiarryth
K channel blockers
39
class 3 antiarryth use
a. fib, a. flutter, Vtach
40
class 4 antiarryth MOA
dec conduction velocity, inc ERP and PR interval
41
class 4 antiarryth
CCB
42
class 4 antiarryth AE
constipation, flushing, edema, CV (HF, AV block, sinus node depression)
43
Class 4 antiarryth use
prevent SVT, Rate control in a. fib
44
Clevidipine is
dihydropyridine CCB works on vasc smooth muscle
45
clevidipine use
HTN urgency/emergency
46
clofibrate is
fibrate
47
colesevelam is a
bile acid resin
48
colestipol is
bile acid resin
49
Dig antidote
anti-dig Fab, Mg also slowly normalizes K
50
dihydropyridine CCB Use
HTN, angina (including prinzmetal), Raynaud
51
Diltiazem is
non-dihydropyridine CCB works on heart
52
Dilt is
class 4 antiarryth CCB
53
Disopyramide is
class 1A antiarryth
54
disopyramide AE
HF, thrombosytopenia, torsades de pointes (inc QT)
55
dofetilide is a
class 3 antiarryth (K channel blocker)
56
ezetimibe MOA
prevent cholesterol abs @ small intestine BBorder
57
ezetimibe use
dec LDL good for pets who don't tolerate statins
58
fenofibrate
fibrate
59
fenoldopam MOA
D1-Rec agonist causes vasoDIL to dec BP and inc natriuresis inc renal perfusion
60
fenoldopam use
HTN emergency
61
fibrates AE
myopathy (inc risk with statins) cholesterol gallstones
62
fibrates MOA
upregulate LPL to inc TAG clearance activate PPARa to induce HDL synthesis
63
fibrate use
dec TAG also mildly dec LDL and inc HDL
64
Flecainide
class 1C antiarryth
65
gemfibrozil
fibrate
66
HTN with DM tx
ACEi/ARB, BB (not in decompensated), aldosterone antagonist ACEi/ ARB protect against diabetic neuropathy
67
HTN w HF tx
diuretics, ACEi, ARB, BB, aldosterone antagonist BB not in decompensated, contra in cardiogenic shock
68
HTN with pregnancy tx
Hydralazine, labetalol, methyldopa, nifedipine
69
Hydralazine AE
reflex tach (prevent with BB), fluid retention, SLE
70
Hydralazine MOA
inc cGMP vasoDIL arterioles (Dec afterload)
71
hydralazine use
severe HTN, HF safe for pregnancy
72
HTN emergency tx
CCB (clevidipine/nicardipine), fenoldopam (D agonist), labetalol, nitroprusside
73
Ibutilide is a
class 3 antiarryth (K channel blocker)
74
Ibutilide AE
torsades de pointes class 3 antiarryth
75
Isosorbide dinitrite is a
nitrate
76
Isosorbide mononitrate is a
nitrate
77
Kawasaki Tx
ASA and IVIg
78
Lidocaine is a
class 1B Antiarryth
79
mexiletine is
class 1B antiarryth
80
Mg use
torsades de pointes, dig toxicity
81
microscopic polyangiitis tx
steroids, cyclophosphamide
82
niacin AE
flushing (tx with NSAID), hyperglycemia, hyperuricemia
83
niacin MOA
inhibit lipolysis in adipose tissue dec VLDL synthesis
84
niacin use
inc HDL also dec LDL and TAG
85
Nicardipine is a
dihydropyridine CCB works on vasc smooth muscle
86
nifedipine is a
dihydropyridine CCB works on vasc smooth muscle
87
nimodipine is a
dihydropyridine CCB
88
nimodipine use
subarach hem (prevent cerebral vasospasm)
89
nitrate MOA
inc NO--> inc cGMP--> venodilation--> dec Preload
90
nitrate use
angina, acute coronary syndrome, pulm edema
91
nitroglycerin is a
nitrate
92
nitroprusside AE
cyanide toxicity
93
nitroprusside MOA
releases NO into inc cGMP, short acting
94
nitroprusside use
HTN emergency
95
non-dihydropyridine CCB use
HTN, angina, a.fib, a flutter
96
polyarteritis nodosa tx
steroids, cyclophosphamide
97
procainamide AE
SLE, thrombocytopenia, torsades de pointes inc QT
98
propafenone is a
class 1C antiarryth
99
quinidine is a
class 1A antiarryth
100
quinidine AE
cinchonism (HA, tinnitus), thrombocytopenia, torsades de pointes (inc QT)
101
sotalol is a
class 3 antiarryth (K Channel blocker)
102
sotalol AE
torsades de points, excess BBlockade
103
statin AE
hepatotoxic (inc LFTs), myopathy (especially with fibrates/niacin)
104
statin MOA
inhibit HMG CoA reductase (cholesterol synthesis)
105
statins use
dec LDL mild inc HDL and dec TAGs dec mortality in CAD pts
106
takayasu arteritis tx
corticosteroids
107
temporal arteritis
hi dose steroids
108
tx for dilated cardiomyopathy
Na restrix, ACEi, BB, diuretic, dig, ICD, heart transplant
109
tx for hypertrophic cardiomyopathy
BB/CCB prolong diastole to inc LV filling to dec obstrux
110
tx for raynaud
CCB
111
tx for STEMI
reperfusion (percutaneous coronary intervention> fibrinolysis) plus hep, ASA, BB, ACEi, nitroglycerin, morphine, statin
112
tx for rheumatic fever
Penicillin
113
type B aortic dissection tx
BB and vasoDIL
114
verapamil is a
class 4 anti arryth (CCB)
115
verapamil is a
nondihydropyridine CCB works on heart
116
verapamil AE
hyperprolactinemia (and other CCB AE)
117
Wegner's tx
steroids, cyclophosphamide

First Aid Pharm (9 decks)

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