Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Drugs - Autonomic > Flashcards

Drugs - Autonomic Flashcards

1
Q

methacholine

A

longer-lasting acetylcholine; methacholine challenge test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

carbachol

A

glaucoma (pupillary constriction and lower intraocular pressure by opening drainage canals)
mainly muscarinic; some nicotinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

pilocarpine

A

glaucoma; more sweating and salivating

mainly muscarinic; some nicotinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

bethanechol

A

promote GI and urinary tract motility

muscarinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

physostigmine

A

reversible cholinesterase inhibitor

glaucoma; anticholinergic overdose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

edrophonium

A

reversible cholinesterase inhibitor

used to distinguish myasthenia gravis from cholinergic crisis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

donepezil

A

reversible cholinesterase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

rivastigmine

A

reversible cholinesterase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

galantamine

A

reversible cholinesterase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

pralidoxime (2-PAM)

A

used to reactivate the phosphorylated acetylcholinesterase before aging occurs. organophosphate poisoning antidote.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

lobeline

A

nicotinic agonist (used for nicotine withdrawal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

arecoline

A

nicotinic agonist (derived from betel nut)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

succinylcholine

A 
nicotinic agonist (paralysis during surgery)
depolarizing blocker
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

atropine

A

muscarinic antagonist; anticholinergic

lo secretions, dilate pupils, hi HR,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

scopolamine

A

muscarinic antagonist; 3º amine

motion sickness, antiemetic, oral secretion management

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

glycopyrrolate

A

muscarinic antagonist; 4º amine

decrease oral secretions, peptic ulcer disease, lo GI spasms, prevent bradycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

ipratropium and tiotropium

A

muscarinic antagonist; 4º amine

respiratory use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

benztropine

A

antimuscarinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

-curonium

A

neuromuscular non depolarizing blocker (nicotinic receptor antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

d-tubocararine

A

neuromuscular non-depolarizing blocker (nicotinic receptor antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

pancuronium

A

long-lasting nicotinic receptor antagonist (think PAN - across it all)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

rocuronium, cisatracurium

A

intermediate nicotinic receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

catecholamine

A

sympathetic agonist; rapid; metabolized by COMT and MAO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

norepinephrine

A

catecholamine; rapid sympathomimetic

acts on a1,a2,b1,b2,b3 (a>b1»b2,b3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

epinephrine

A

catecholamine; rapid sympathomimetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

dopamine

A

catecholamine; rapid sympathomimetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

isoproterenol

A

catecholamine; rapid sympathomimetic; synthetic

28
Q

dobutamine (racemic)

A

catecholamine; rapid sympathomimetic; synthetic

29
Q

phenylephrine

A

a1-selective adrenergic agent

vasoconstriction - may cause reflex bradycardia parenterally, can be used for mydriasis

30
Q

clonidine

A

a2-selective adrenergic agent
(CNS: INHIBITS exhitatory outflow from neurons of CV centres; posynaptic receptor)
(PNS: INHIBITS release of catecholamines from postganglionic sympathetic neurons; presynaptic)

31
Q

dobutamine

A

b1 selective adrenergic agonist (d-isomer). L-isomer is a weak b1 agonist and potent a1 agonist.

32
Q

salbutamol

A

b2 adrenergic agonist (short)

33
Q

salmeterol

A

b2 adrenergic agonist (long)

34
Q

metaproterenol

A

b2 adrenergic agonist

35
Q

terbutaline

A

b2 adrenergic agonist (short)

36
Q

formoterol

A

b2 adrenergic agonist (long)

37
Q

isoproterenol

A

non-selective beta blocker; rarely used because nonselective

38
Q

amphetamine

A

indirect adrenergic agent (NE release)

39
Q

tyramine

A

indirect adrenergic agent (NE release)

40
Q

cocaine

A

indirect adrenergic agent (lo NE reuptake)

41
Q

tricyclic antidepressant

A

indirect adrenergic agent (lo NE reuptake)

42
Q

ephedrine

A

mixed sympathomimetic

43
Q

pseudoephedrine

A

mixed sympathomimetic for nasal/sinus congestion

44
Q

a-methyl-p-tyrosine

A

indirect sympatholytic

decrease synthesis

45
Q

reserpine

A

indirect sympatholytic

decrease storage via vesicular monoamine transporter VMAT inhibition

46
Q

guanethidine

A

indirect sympatholytic

decrease release

47
Q

phentolamine

A

reversible a-adrenergic receptor antagonist. nonselective.

48
Q

prazocin

A

reversible a-adrenergic receptor antagonist

49
Q

phenoxybenzamine

A

irreversible a-adrenergic receptor antagonist. nonselective.

50
Q

-osin

A

a1-selective adrenergic antagonist

51
Q

tamsulosin

A

a1-selective antagonist, selective for a1A receptors in the prostate. doesn’t affect a1B (in CV system)

52
Q

propanolol

A

nonselective beta blocker

53
Q

timolol

A

nonselective beta blocker. potent. usually topical for eye.

54
Q

nadolol

A

nonselective beta blocker. potent.

55
Q

labetalol

A

blocker for b1, b2, a1.

56
Q

metoprolol

A

b1 blocker

57
Q

atenolol

A

b1 blocker

58
Q

bisoprolol

A

b1 blocker

59
Q

esmolol

A

b1 blocker. short half life.

60
Q

carbamazepine

A

voltage-gated sodium channel inactivation stabilizer

61
Q

muscarine

A

cholinergic agonist

62
Q

-stigmine

A

acetylcholinesterase inhibitor

63
Q

diphenhydramine

A

anticholinergic (benadryl)

64
Q

dimenhydrinate

A

anticholinergic (gravol)

65
Q

benztropine

A

anticholinergic

66
Q

benzodiazepine

A

sedative. (enhance GABA)

Pharmacology (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions