Drug Names Flashcards
1
Q
Celecoxib
A
Celebrex
2
Q
Zileuton
A
Zyflow
3
Q
Zileuton - mechanism
A
5-LO inhibitor
4
Q
Celecoxib mechanism
A
Specific COX2 inhibitors
5
Q
Montelukast
A
Singulair
6
Q
Montelukast mechanism
A
CystLT1 receptor antagonist
7
Q
Omalizumab
A
Xolair
8
Q
Omalizumab mechanism
A
Binds free IgE from binding to FCeRI on mast cells and basophils
9
Q
Omalizumab effects
A
- Increase total IgE but decrease free IgE
- Decreases eosinophil
- Decreases expression of FceRI
- Decreases FeNO (less circulating IL-13)
- Decreases mediator release from mast cells and basophils
- Decreases urine LTE4 and PGD2 in AERD
10
Q
Mepolizumab
A
Nucala
11
Q
Dupilumab
A
Dupixent
12
Q
Benralizumab
A
Fasenra
13
Q
Mepolizumab mechanism
A
Binds to IL5 and prevents it from binding to the alpha chain of the receptor complex
14
Q
Benralizumab
A
Binds to the alpha chain of the IL5 receptor
