Drug Interactions from the College Flashcards

1
Q

CYP1A2 inducers

A

Omeprazole

Tobacco

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2
Q

CYP2B6 inducers

A

Barbituates

Rifampicin

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3
Q

CYP2C19 inducers

A

Rifampicin
Prednisolone
Carbamazepine

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4
Q

CYP2E1 inducers

A

Ethanol

Isoniazid

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5
Q

CYP3A4 inducers

A
Phenytoin
Carbamazepine
Barbituates
Rifampicin
Glucocorticoids
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6
Q

Drug interaction: phenytoin and vecuronium

A

Enzyme inducer - reduced duration of neuromuscular blockade

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7
Q

Drug interaction: carbemazepine and vecuronium

A

Enzyme inducer - reduced duration of neuromuscular blockade

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8
Q

Drug interaction: rifampicin and warfarin

A

Enzyme inducer - reduced efficacy of warfarin

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9
Q

Drug interaction: carbemazipine and warfarin

A

Enzyme inducer - reduced efficacy of warfarin

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10
Q

Drug interaction: rifampicin and ciclosporin

A

Enzyme inducer - reduced efficacy of ciclosporin

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11
Q

Drug interaction: barbituates and corticosteroids

A

Enzyme inducer - reduced efficacy of corticosteroids

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