DNA replication Flashcards

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1
Q

DNA helicase

A

enzyme that unzips the DNA

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2
Q

DNA polymerase

A

enzyme that connects a strand of DNA to another to form a complete helix

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3
Q

replication fork

A

the ends of each replication bubble

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4
Q

replication bubble

A

the origins of the DNA helicase unzipping the DNA

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5
Q

prokaryotes form how many rep. bubbles?

A

one

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6
Q

eukaryotes form how many rep. bubbles?

A

multiple

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7
Q

semiconservative model of replication

A

separated strands act as templates for a new complementary strand to form two DNA helix’s

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8
Q

DNA polymerase can only add new nucleotides to the

A

3’ ends- strands will be built in a 5’ to 3’ direction

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9
Q

prokaryotic DNA rep.

A

since the strand is like a ring there is only one bubble that goes in two directions

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10
Q

which enzyme proofreads DNA

A

Exonuclease and polymerase

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11
Q

how many mistakes are made in base pairs?

A

1 in 10000

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12
Q

how many mistakes in base pairs after correction?

A

1 in 1 billion

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13
Q

what damage DNA?

A

chemicals and radiation

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14
Q

excision repair

A

when any of over 50 repair enzymes remove damages pairs of DNA

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15
Q

role of DNA ligase and polymerase in excision repair

A

they insert and bond the new nucleotides together after the damaged DNA is taken out

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