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Embryo Finals > Development Of Special Senses > Flashcards

Development Of Special Senses Flashcards

1
Q

Outer layer of optic cup

A

Pigment epithelium

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2
Q

Cornea is naked ( no eyelids, except for primordium)

A

42 days pc

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3
Q

Eyelids have grown over the cornea

A

77 days pc

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4
Q

Eyelids separate to form the

A

Palpebral fissure

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5
Q

Rapid optic nerve vascularization

A

12-14 wks pc

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6
Q

Dura matter first appears around optic nerve

A

Wk 15

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7
Q

Immunoreactivity for glial fibrillary acidic protein first appears in optic nerve

A

Wk 24?

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8
Q

First myelinated fibers seen in intracranial part of optic nerve. Immunoreactivityor myelin basic protein appears in optic nerve

A

Wk 31-32

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9
Q

First myelinated fibers seen in retrobulbar optic nerve

A

Wk 40

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10
Q

Myelination of optic nerve proceeds to from chiasm to bulb

A

Week 32-40 and beyond

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11
Q

The eyes are fused in the midline, because loss of midline structures has prevented the eye fields from separating

A

Synophthalmia

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12
Q

postural muscles in the muscular compartment of the neck

A

Coloboma

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13
Q

Lens opacification

May occur with developmental rubella infection

A

Congenital cataract

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14
Q

May occur in developmental rubella or cytomegalovirus infection or be due to maternal alcohol infection

A

Microphthalmia (small eye)

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15
Q

Origin of the external auditory meatus

A

1st pharyngeal cleft

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16
Q

Origin of the auricle

A

Ectoderm and mesenchyme of 1st and 2nd arches

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17
Q

External ear

A

External auditory meatus

Auricle

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18
Q

Middle ear

A

Tympanic cavity and eustachian tube
Malleus and incus
Stapes

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19
Q

Origin of the tympanic cavity and eustachian tube

A

1st pharyngeal pouch

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20
Q

Origin of the malleus and incus

A

1st arch cartilage

21
Q

Origin of the stapes

A

2nd arch cartilage

22
Q

Origin of the membranous labyrinth (inner ear)

A

Otic vesicle

23
Q

Origin of the statoacoustic ganglion (inner ear)

A

Neural crest and otic vesicle

24
Q

Otic placode (surface ectoderm) invaginates

A

28 days pc

25
Q

Invaginating placode

A

24 days pc

26
Q

Otic pit

A

27 days pc

27
Q

Otic vesicle

A

32 days pc

28
Q

External ear abnormalities (ear tags) may indicate

A

Chromosomal abnormalities

29
Q

Olfactory pit forms bet the medial and lateral nasal processes

A

32 days pc

30
Q

What develops in the depths of the olfactory pit?

A

Olfactory placode (olfactory epithelium primordium)

31
Q

major source of gonadotropin releasing hormone (GnRH) producing cells for hypothalamus

A

Vomeronasal organ & terminal nerve

32
Q

GnRH can be detected in human olfactory epithelium as early as

A

5.5 weeks

33
Q

Migra;on of GnRH cells along the developing vomeronasal/terminal nerve complex occurs during

A

Wk 6-8

34
Q

Hypogonadotrophic hypogonadism associated with reproduction dysfunction

A

Kallmann syndrome

35
Q

the olfactory, vomeronasal and terminal nerves terminate in the meninges and do not enter the brain

A

Kallmann syndrome

36
Q

Two genes resp for kallmann’s syndrome

A

KAL1 & KAL2

37
Q

encodes anosmin 1, present along the migration path of GnRH neurons and the central roots of the terminal nerve

A

KAL1

38
Q

encodes fibroblast growth factor receptor 1 (FGFR1)

A

KAL2

39
Q

lack of functioning olfaction; an inability to perceive odors.

A

Anosmia

40
Q

the loss of taste functions of the tongue, particularly the inability to detect sweetness, sourness, bitterness, saltiness, and umami

A

Ageusia

41
Q

Development of the optic vesicles starts from a progressively deepening groove in the neural plate called the optic sulcus.

A

Week 3

42
Q

The optc vesicles come into contact with the epithelum and induce the epidermis which will thicken to form the ——

A

lens placode

43
Q

migrates in during the forma;on of the op;c cup and is critical for the induction of the retinal pigment epithelium and the optic nerve.

A

Periocular mesenchyme

44
Q

The human ear develops from the auditory placode

A

Wk 4

45
Q

a thickening of the ectoderm that gives rise to the bipolar neurons of the cochlear and vestibular ganglions

A

Auditory placode

46
Q

The auditory vesicle will five rise to

A

Uricular and saccular components of the membranous labyrinth

47
Q

the auditory vesicle also gives rise to the cochlear duct, which contains the spiral organ of Corti and the endolymph that accumulates in the membranous labyrinth

A

Wk 5

48
Q

Neurons in the vestibular system mature during the

A

First 2-3 postnat weeks

49
Q

Inner layer of optic cup

A

Sensory retina (neurons and photoreceptors)

Embryo Finals (5 decks)

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