Development of Respiratory System Flashcards

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1
Q

What determines location of lung bud?

A

Retinoic acid in mesoderm of foregut

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2
Q

How many rounds of division do bronchial buds undergo?

A

approx 16

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3
Q

Up until what age do additional terminal sacs continue to form and differentiate

A

2 yrs

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4
Q

When do terminal bronchioles divide into respiratory bronchioles?

A

Weeks 16-28

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5
Q

When is there a sufficient number of capillaries present to guarantee gaseous exchange?

A

weeks 28-36

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6
Q

Name the 2 types of alveolar epithelial cells and their functions

A

Type I- Surface for gaseous exchange

Type II- Produce surfactant

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7
Q

Outline respiratory distress disease

A
  1. Inadequate surfactant production
  2. Can result in hyaline membrane disease
  3. Treated with surfactant replacement therapy
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8
Q

Where does the bronchi enter the lung?

A

hilum

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9
Q

What vertebrae does trachea extend from/to?

A

CVI- TIV/V

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10
Q

Which bronchus is larger?

A

Right one

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11
Q

list the parts from bronchus

A

Bronchus
lobar bronchi
segmental bronchi
bronchioles

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12
Q

What are the surfaces of the lung?

A

Apex
Base (diaphragmatic surface)
Costal surface
Mediastinal surface

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13
Q

How many lobes and fissures does right lung have?

A

3 lobes

2 fissures

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14
Q

How many lobes and fissures does left lung have?

A

2 lobes

1 fissure

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15
Q

What are bronchopulmonary segments?

A

Smallest functionally independent region of a lung

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16
Q

What period is canalicular stage?

A

weeks 16-28

17
Q

What period is saccular stage?

A

weeks 28-36

18
Q

What period is alveolar stage?

A

weeks 36-term

19
Q

What happens in alveolar stage?

A

Formation of mature alveoli

20
Q

When are the remaining alveoli formed?

A

First 8-10yrs