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phuck farm final > depressed for this final > Flashcards

depressed for this final Flashcards

1
Q

SIGECAPS (symptoms)

A

Sleep, Interest, Guilt, Energy, Concentration, Appetite, Psychomotor, Suicidal

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2
Q

APA 2010 guidelines 1st line:

A

SSRI, SNRI, Buproprion, Mirtazapine (4 weeks for full effects)

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3
Q

ACP 2016 guidelines for major depressive disorder:

A

CBT or SGA

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4
Q

Black box warning for all anti-despressants:

A

suicide

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5
Q

Seritonin syndrome:

A

-too much serotonin
symptoms: mental status change (agitation, hallucinations, coma
Autonomic instability: tachycardia, HTN, hyperthermia

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6
Q

SSRI major risk:

A

-increased bleed risk

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7
Q

Fluoxetine (prozac) indications:

A

Major Depressive disorder
Obsessive compulsive disorder
Parkinsons
Bulimia

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8
Q

Fluoxetine ADRs:

A
  • Monitor with triptans,

- Least weight gain

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9
Q

Fluoxetine DIs:

A

CYP 2D6 inhibitor

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10
Q

Paroxetine (PAXIL) indictations:

A
  • Major depressive disorder
  • Obsessive compulsive disorder
  • general anxiety
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11
Q

Paroxetine ADRs:

A
  • sedating
  • Bad sex
  • get fat
  • anticholenergics
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12
Q

Paroxetine DIs;

A

CYP 2D6 inhibitor

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13
Q

Sertraline (Zoloft) Indications:

A 
major depressive disorder
obsessive
social anxiety
parkinsons
PTSD
post-menopausal depression
-benefits its with CV dz
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14
Q

Sertraline ADR:

A

sedation/insomnia

  • bad sex
  • dry mouth
  • tremor
  • dizzy
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15
Q

Escitalopram (lexapro) indications:

A

major depression
general anxiety
-use in meds and adolescents

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16
Q

Escitalopram ADRS:

A

sedation/insomnia
sexual side effects?
nausea

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17
Q

Citalopram (celexa) indications

A

-depression

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18
Q

citalopram warning:

A

long QT

-lowest risk of bad sex

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19
Q

SSRIs:

A
  • Fluoxetine
  • paroxetine
  • sertraline
  • escitalopram
  • citalopram
  • vortioxetine
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20
Q

vortioxetine (trintellix) indications:

A

Major depression

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21
Q

vortioxetine DIs:

A

CYP 2D6

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22
Q

Serotonin-Norepinephrine reuptake inhibitors:

A

venlafaxine, desvenlafaxine, duloxetine, milnacipran, levomilnicipran

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23
Q

venlafaxine (Effexor):

A

-major depression
-general anxiety
social anxiety
parkinsons
-chronic pain

24
Q

venlafaxine ADRs:

A

N/C/D (constipated diarrhea is the worst), HA, dry mouth, sweating, somnolence, insomnia, dizzy, bad sex

25
Q

venlafaxine DIs:

A
  • triptans, tramadol, tryptophan, SSRIs, st. johns wort, lithium, fentanyl
  • NSAID, ASA, Warfin bleeding risk
26
Q

Desvenlafaxine Indications:

A

-major depression

27
Q

desvenlafaxine ADRs:

A

N, dry mouth, sweating, somnolence, insomnia, fatigue, dizzy, bad sex

28
Q

Duloxetine indications:

A

major depression, general anxiety, neuropathic pain, chronic pain, fibromyalgia

29
Q

duloxetine warning:

A

serotonin syndrome, bleeding, orthostasis, hyponatremia, avoid with liver impairment

30
Q

duloxetine ADRs:

A

N/C, dry mouth, sweating, somnolence, decreased appetite

31
Q

fluoxetine DIs:

A

MAOIs

32
Q

Milnacipran indications:

A

fibromyalgia

33
Q

milnacipran warning:

A

serotonin

bleeding, hen, tachycardia, sz

34
Q

milnacipran ADR:

A

N/V/C. HA, dry mouth, sweating, hot flashes, insomnia, inc. hr, palpitation, htn, dixxi

35
Q

milnacipran DIs:

A
  • seritonin drugs

- MAOIs

36
Q

Levomilnicipran indications

A

Major depression

37
Q

levomilnicipran warning:

A

-seritonin syndrome, bleeding, hen, tachycardia, sz

38
Q

levomilnicipran adrS:

A

n/v/c, sweating, inc. hr, tachycardia, palpitations, no boners

39
Q

levomilnicipran DIs:

A

-seritonin drugs
Maoi’s
3a4s

40
Q

atypical antidepressants:

A

mirtazepine, bupropion

41
Q

mirtazepine Indications:

A

major depression

42
Q

Mirtazepine warning:

A

avoid EtOH and other depressants

43
Q

mirtazepine ADR:

A 
-wt gain
sedation
somnolence (caution driving)
dizzy
orthostasis
inc cholesterol and lfts
granulocytosis
44
Q

bupropion indications:

A

mdd

smoking cessation

45
Q

bupropion warning:

A

sz

  • eating disorder
  • withdrawl or EtOH or sedatives
46
Q

bupropion ADrs:

A

lose weight

n/v, ha, dry mouth, insomnia, agitation, anxiety, psychosis, delusions, hallucinations, confusion, htn

47
Q

tricyclic antidepressants:

A

amitriptyline
doxepin
imipramine
desipramine

48
Q

tricyclics MOA:

A

SNRI, anticholenrgic

49
Q

tricyclics indications:

A

depression, anxiety, bipolar, ocd, neuropathic pain, migraine prophylaxis

50
Q

tricyclics warning:

A
  • intentional OD
  • sz, hypotension, palpitation, convulsion, dec. mental status, respiratory depression, drowsiness
  • anticholenergic
51
Q

tricyclics adr:

A

anticholenergics

52
Q

tricyclic dis:

A 
SSRIs
MAOIs
anticholenergics 
sympathomimetics
cimetidine
53
Q

5-ht modulators:

A

trazadone, vilazodone

54
Q

5-ht modulators indications

A

depression

55
Q

5-ht modulator ADRs:

A

ha, sedation, somnolence, dry mouth, dizziness, orthostasis, long qt, arrhythmia, stuck boner

56
Q

last line depression meds?

A

MAOIs

57
Q

antidepression supplements:

A

st. johns wort

phuck farm final (5 decks)

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