Denise

Question 1

What is the pharmacology, action, rationale and nursing responsibility for Aspirin?

Answer 1

Pharmacology: NON SELECTIVE COX inhibitor which inhibits the production of thromboxane A2 and therefore platelet aggregation and clot formation. Inhibits prostaglandin synthesis and thus, inflammation, temp and pain
Action: Antipyretic, antiplatelet, analgesic, anti-inflammatory
Rationale: hyperlipidaemia, AF, hypertension which can all lead to platelet aggregation and clotting
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, other antiplatelets/COX inhibitors, MONITOR BP IF GIVEN WITH B-BLOCKER

Question 2

What is the pharmacology, action, rationale and nursing responsibility for Atorvastatin?

Answer 2

Pharmacology: inhibits HMG-COA reductase which decreases cholesterol synthesis
Action: decreases lipid production
Rationale: hyperlipoidemia
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, liver/hepatic function, cardiac symptoms associated with hyperlipidaemia, MAY INCREASE DIGOXIN SERUM LEVELS = TOXICITY, CAUSES INSOMNIA, don’t crush

Question 3

What is the pharmacology, action, rationale and nursing responsibility for Glyceryl Trinitrate?

Answer 3

Pharmacology: increases O2 supply by causing vasodilation.
Action: increases oxygenation supply to the heart, decreasing ischemia and pain
Rationale: chest pain
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, liver/hepatic function, don’t give if have tachycardia or hypotension, if given with ASPIRIN ITS EFFECTS DECREASE

Question 4

What is the pharmacology, action, rationale and nursing responsibility for Morphine?

Answer 4

Pharmacology: block opioid receptors in the brain and spinal cord and inhibits presynaptic neurotransmitter release
Action: decrease pain transmission
Rationale: moderate - severe pain due fracture and ICC insertion/wound site
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, monitor for resp depression, urinary retention, dependence, intracranial pressure, 2 nurse check, book, keep antagonist naloxone available, assess pain score, baseline obs before

Question 5

What is the pharmacology, action, rationale and nursing responsibility for metoclopramide?

Answer 5

Pharmacology: blocks dopamine, preventing gastric smooth muscle relaxation and increases gastric emptying
Action: antiemetic - treats nausea and vomiting
Rationale: nausea from opioid and post op
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, hepatic/renal impairment, assess for extrapyramidal symptoms

Question 6

What is the pharmacology, action, rationale and nursing responsibility for Lercanidipine hydrochloride?

Answer 6

Pharmacology: calcium channel blocker which reduces contraction and therefore causes vasodilation which reduces afterload and the work of heart
Action: antihypertensive - decreases BP
Rationale: hypertension, MI - to prevent another
Nursing Responsibilities: 5 moments of hand hygiene, 8 rights of medication administration + allergies, check drug guide to ensure knowledge, ensure patient knowledge, hepatic/renal impairment, don’t give if hypotensive, caution if with B-BLOCKER, ANTIHYPERTENSIVES, NITRATES