Deel 6 Flashcards by Lore Wils | Brainscape

Q

cyproterone acetaat

A

progesteron derivaat, pregnanes

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Q

medroxyprogesteron acetaat

A

progesteron derivaat, pregnanes

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Q

chlormadinone acetaat

A

progesteron derivaat, pregnanes

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Q

nomegestrol acetaat

A

progesteron derivaat, pregnanes

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Q

dienogest

A

C19 nortesterone, estranes

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Q

norethindrone

A

C19 nortesterone, estranes, 1ste generatie

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Q

norethisterone acetaat

A

C19 nortesterone, estranes, 1ste generatie

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Q

ethynodiol diacetate

A

C19 nortesterone, estranes, 1ste generatie

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Q

lynestrenol

A

C19 nortesterone, estranes, 1ste generatie

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Q

norethynodrel

A

C19 nortesterone, estranes, 1ste generatie

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Q

norgestrel

A

C19 nortesterone, gonanes, 1ste generatie

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Q

levonorgestrel

A

C19 nortesterone, gonanes, 2de generatie

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Q

norgestimate

A

C19 nortesterone, gonanes, 2de generatie

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Q

desogestrel

A

C19 nortesterone, gonanes, 3de generatie

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Q

gestodene

A

C19 nortesterone, gonanes, 3de generatie

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Q

drosperidone

A

spironolacton derivaat

in anticonceptie als progestageen

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Q

amikacine

A

AB, aminoglycosiden

monitoring

Q

kanamycine

A

AB, aminoglycosiden

monitoring

Q

gentamicine

A

AB, aminoglycosiden
monitoring
polykationen: niet geabsorbeerd per oraal
Na parenterale toediening: enkel hoge conc niercortex
Renale excretie

AE: ototoxiciteit, nefrotoxiciteit, curare effect neuromusculaire blok

Q

paromomycine

A

AB, aminoglycosiden

monitoring

Q

tabramycine

A

AB, aminoglycosiden
monitoring

AE: oto en nefrotox., curare effect

Q

spectinomycine

A

AB, aminoglycosiden
monitoring

AE: oto en nefrotoxiciteit, curare effect

Q

streptomycine

A

AB, aminoglycosiden
monitoring
niet in België

Q

minocycline

A

AB, tetracyclines

Q

doxycycline

A

AB, tetracyclines
Bij ziekte van Lyme

volledige absorptie, goede weefseldistributie en penetratie, renale klaring

AE: fotosensitiviteit, fanconi-syndroom, platte groengele stoelgang, epigastrische last, slokdarmulcera, refluxoesofagitis, beninge intracraniële hypertensie, levertoxiciteit,…

Q

chlooramfenicol

A

AB
zeer goede orale biologische beschikbaarheid
goede weefseldistributie, ook in CZS

AE: aplastische anemie, gestoorde rijping van de RBC in beenmerg, gray baby syndroom

Q

erythromycine

A

AB, macroliden

CYP3A4 inhibitor

AE: nausea, braken, diarree, QT verlenging

Q

claritromycine

A

AB, macroliden

CYP3A4 en p-gp inhibitor

AE: nausea, braken, diarree, QT verlenging

Q

azitromycine

A

AB, macroliden

Q

clindamycine

A

AB

leidt tot clostridium difficili infectie met psuedomembraneuze colitis

Q

linezolide

A

AB

Q

cotrimoxazol

A

AB

combinatie sulfamide en trimethoprim

Q

chinolonen

A

AB

Q

penicilline

A

AB
absorptie afh zuurweerstandigheid en mate van eiwitbinding
goede distributie behalve CZS
renale excretie

AE: allergische reactie (en anafylactische shock)

Q

vancomycine

A

AB
Bij clostridium difficile
oraal slechte absorptie

AE: oto- en nefrotoxiciteit, red neck syndroom

Q

teicoplanine

A

AB

Q

nimorazol

A

AB, nitro-imidazoolderivaten

AE: droge mond, metaalsmaak, hoofdpijn, disulfiram effect

Q

metronidazole

A

AB

CYP2C9 inhibitor

AE: droge mond, metaalsmaak, hoofdpijn, disulfiram effect

Q

ornidazol

A

AB, nitro-imidazoolderivaten

AE: disulfiram effect, droge mond, metaalsmaak, hoofdpijn

Q

tinidazol

A

AB, nitro-imidazoolderivaten

AE: disulfiram effect, metaalsmaak, hoofdpijn, droge mond

Q

rifampicine

A

AB

tuberculose

Q

azoolantimycotica

A

tegen dermatofyten en andere schimmels