Daniels Flashcards
What are some defining characteristics of s. Pneumoniae?
ENCAPSULATED gram +
What does s. Pneumoniae cause?
Community acquired pneumonia
How do you treat pneumococcus?
Penicillin and other beta-lactams
What are some characteristics of legionella pneumophila?
- Gram -
- Special conditions for cultivation
- Cysteine requirement
How do we encounter L. Pneumophila?
DIRTY WATER
What are some virulence factors of L. Pneumophila?
- Survival in macrophages
2. LPS and flagellin
How to treat L. Pneumophila?
No penicillin
Intracellular penetration antimicrobials
What does b. Pertussis cause?
Whooping cough
How does b. Pertussis cause damage?
- Pertussis toxin
- Adenylate Cyclades
Upregulate cAMP -> decrease neutrophil function
What causes tuberculosis and leprosy?
Mycobacterium spp.
What do mycobacterium spp form?
Granuloma
T/F: M. Leprae is able to be cultivated in vitro.
FALSE
Can not be cultivated