CV pharmacology intro Flashcards

1
Q

Most antidysrhythmics tend to be negative chrontropes. What do chronotropes alter?

A

Heart rate

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2
Q

What do inotropes alter?

A

Contractility

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3
Q

What do dromotropes alter?

A

Conduction speed of AVN

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4
Q

What do lusiotropes alter?

A

Relaxation of myocardium

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5
Q

Heart rate is altered where and by which nervous system?

A

CV centre in medulla oblongata

Autonomic nervous system

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6
Q

Cardiomyocytes work as syncytium - what does this mean?

A

Work as one - connected by intercalated discs

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7
Q

The conduction of an AP is reliant on which cations and their channels?

A

Na
K
Ca

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8
Q

Why may conduction of APs (and therefore HR) be dysfunctional?

A

Ectopic pacemaker
Damage to conducting tissue
Depression of CV centre (e.g. anaesthesia)

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