CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE) Flashcards
Shelflife, Thawed, and Pooled of CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR
> Frozen – 1 year
Thawed – 6 hours
Pooled – 4 hours
What is cryoprecipitate?
> Cryoprecipitate is a preparation rich in clotting factors of fibrin glue
How many Celcius in the storage temp for CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)
> Frozen= -18ºC or colder
Thawed – 20-24ºC
Give the contents about CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)
> Factor VIII:C - 80-150 IU
Factor VIII:vWF : 40 – 70 %
Fibrinogen – 150-250mg
Factor XIII : 20 – 30 %
Give the Indications about CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)
> Hemophilia A, von Willebrand’sdse, Fibrinogen deficiency, Factor XIII deficiency
What is the purpose of Fibrin Glue when used in surgery with thrombin reagent?
- Fibrin Glue, composed of an equal mixture of cryoprecipitate and thrombin reagent, serves as a topical application in surgical procedures.
- Its primary function is to effectively halt hemorrhagic bleeding at the surgical site.
What coagulation factors are present in cryoprecipitate?
- Factor 1 (Fibrinogen) and Factor 13.