Congenital bleeding disorders

Question 1

Which factors contribute to the intrinsic pathway?

Answer 1

VIII, IX, XI, XII

Question 2

Which factors contribute to the extrinsic pathway?

Answer 2

VII

Question 3

Which conditions cause isolated prolonged PT?

Answer 3

Liver disease, warfarin, apixaban, isolated factor VII deficiency

Question 4

Causes of combined prolong PT and APTT?

Answer 4

Liver disease, malabsorption, warfarin, DIC, factor deficiencies

Question 5

Which factor is deficient in haemophilia A? What is the mode of inheritence?

Answer 5

VIII, X-linked recessive

Question 6

Which factor is deficient in haemophilia B? What is the mode of inheritence?

Answer 6

IX, x linked recessive

Question 7

Haemophilia C?

Answer 7

XI, AR