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DISPENSING LEC (DRUG INTERACTION) > Common drug toxicities > Flashcards

Common drug toxicities Flashcards

1
Q

Clozapine

A

Agranulocytosis

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2
Q

Chloramphenicol
NSAIDs
Benzene

A

Aplastic Anemia

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3
Q

Tricyclics (TCA’s)

A

Atropine-like Side Effects

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4
Q

Doxorubicin
Daunorubicin

A

Cardiotoxicity

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5
Q

Fluoroquinolones (Ciprofloxacin & Norfloxacin)

A

Cartilage Damage in
children

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6
Q

Quinidine

A

Cinchonism

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7
Q

ACE Inhibitors

A

Dry Cough

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8
Q

Lithium

A

Diabetes Insipidus

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9
Q

Metronidazole
Sulfonylureas (1st generation)

A

Disulfiram-like effect

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10
Q

Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)

A

Extrapyramidal Side
Effects

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11
Q

Tetracycline

A

Fanconi’s Syndrome

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12
Q

Valproic Acid
Halothane
Acetaminophen

A

Fatal Hepatotoxicity
(necrosis)

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13
Q

Phenytoin

A

Gingical Hyperplasia

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14
Q

Chloramphenicol

A

Gray Baby Syndrome

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15
Q

Cimetidine
Azoles
Spironolactone
Digitalis

A

Gynecomastia
Cimetidine
Azoles
Spironolactone

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16
Q

Sulfonamides
Isoniazid
Aspirin

A

Hemolytic Anemia in
G6PD-deficiency

17
Q

Isoniazid

18
Q

Niacin
Tamoxifen
Ca++ Channel Blockers (CCB’s)

A

Hot Flashes, Flushing

19
Q

Barbiturates
Phenytoin
Carbamazepine
Rifampin

A

Induce CYP450

20
Q

Cimetidine
Ketoconazole

A

Inhibit CYP450

21
Q

Methicillin
NSAIDs (except Aspirin)
Furosemide
Sulfonamides

A

Interstitial Nephritis

22
Q

Nitroglycerin Industrial exposure —-> tolerance during week —-> loss

A

Monday Disease

23
Q

Rifampin

A

Orange Body Fluids

24
Q

Heparin
Corticosteroids

A

Osteoporosis

25
Q

Methyldopa

A

Positive Coombs’ Test

26
Q

Bleomycin
Amiodarone

A

Pulmonary Fibrosis

27
Q

Vancomycin

A

Red Man Syndrome

28
Q

MAOIs

A

Severe HTN with
Tyramine

29
Q

Procainamide
Hydralazine

A

SLE-like Syndrome

30
Q

Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine)

A

Tardive Dyskinesia

31
Q

Aspirin
Quinidine

DISPENSING LEC (DRUG INTERACTION) (7 decks)

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