Classical CNS Neurotransmitters Flashcards

1
Q

List three types of type II neurotransmitters.

A

Catecholamines, amines, purines

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2
Q

What receptor type do type II and III neurotransmitters usually use?

A

G-protein coupled

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3
Q

What time of receptor does 5HT-3 receptor use?

A

Ionotropic

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4
Q

What neurotransmitters are common in the cortex?

A

Noradrenaline, Ach, dopamine and 5-HT

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5
Q

What neurotransmitter is common in the striatum?

A

Dopamine

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6
Q

What neurotransmitter is common in the n. accumbens?

A

Dopamine, 5-HT

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7
Q

What neurotransmitters are common in the hippocampus?

A

5-HT, Ach, dopamine

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8
Q

What neurotransmitters are common in the amygdala?

A

5-HT, dopamine, noradrenaline

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9
Q

What neurotransmitter is common in the hypothalamus?

A

Dopamine

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10
Q

Name an noradrenaline uptake 1 inhibitor.

A

Desipramine

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11
Q

Name a dopamine transporter inhibitor.

A

Cocaine

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12
Q

Name a SERT inhibitor.

A

Fluoxetine prozac

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13
Q

Which neurotransmitters does MAO-A metabolise?

A

Noradrenaline and 5-HT

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14
Q

Which neurotransmitter for MAO-B metabolise?

A

Dopamine

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15
Q

Where are noradrenergic cell bodies located?

A

Locus coeruleus (LC)

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16
Q

How does LSD work?

A

Activates 5-HT receptors

17
Q

Where are 5-HT cell bodies located?

A

In the raphe nucleus

18
Q

How does reserpine work?

A

Depletes monoamines

19
Q

Which drug inhibits MAO-A?

A

Pargyline

20
Q

How does pargyline work?

A

Inhibits MAO-A

21
Q

What is the noradrenergic receptor in the frontal cortex?

A

Beta 1

22
Q

What are the noradrenergic receptors in the prefrontal cortex?

A

Alpha 1 and 2

23
Q

What are the noradrenergic receptors in the limbic cortex?

A

Beta 1, alpha 1 and 2