Classical CNS Neurotransmitters Flashcards
List three types of type II neurotransmitters.
Catecholamines, amines, purines
What receptor type do type II and III neurotransmitters usually use?
G-protein coupled
What time of receptor does 5HT-3 receptor use?
Ionotropic
What neurotransmitters are common in the cortex?
Noradrenaline, Ach, dopamine and 5-HT
What neurotransmitter is common in the striatum?
Dopamine
What neurotransmitter is common in the n. accumbens?
Dopamine, 5-HT
What neurotransmitters are common in the hippocampus?
5-HT, Ach, dopamine
What neurotransmitters are common in the amygdala?
5-HT, dopamine, noradrenaline
What neurotransmitter is common in the hypothalamus?
Dopamine
Name an noradrenaline uptake 1 inhibitor.
Desipramine
Name a dopamine transporter inhibitor.
Cocaine
Name a SERT inhibitor.
Fluoxetine prozac
Which neurotransmitters does MAO-A metabolise?
Noradrenaline and 5-HT
Which neurotransmitter for MAO-B metabolise?
Dopamine
Where are noradrenergic cell bodies located?
Locus coeruleus (LC)
How does LSD work?
Activates 5-HT receptors
Where are 5-HT cell bodies located?
In the raphe nucleus
How does reserpine work?
Depletes monoamines
Which drug inhibits MAO-A?
Pargyline
How does pargyline work?
Inhibits MAO-A
What is the noradrenergic receptor in the frontal cortex?
Beta 1
What are the noradrenergic receptors in the prefrontal cortex?
Alpha 1 and 2
What are the noradrenergic receptors in the limbic cortex?
Beta 1, alpha 1 and 2
