Classic/Relevant Treatments

Question 1

Absence seizures

Answer 1

Ethosuximide

Question 2

Acute gout attack

Answer 2

NSAIDS, colchicine, glucocorticoids

Question 3

Acute promyelocytic leukemia (M3)

Answer 3

All trans-retinoic acid

Question 4

ADHD

Answer 4

Methylphenidate, amphetamines, CBT, atomoxetine, guanfacine, clonidine

Question 5

Alcoholism

Answer 5

Disulfiram, acamprosate, naltrexone, supportive care

Question 6

Alcohol withdrawl

Answer 6

Long-acting benzodiazepines

Question 7

Anorexia

Answer 7

Nutrition, psychotherapy, mirtazapine

Question 8

Arrhythmia in damaged cardiac tissue

Answer 8

Class 1B antiarrhythmic (lidocaine, mexiletine)

Question 9

Benign prostatic hyperplasia

Answer 9

alpha 1 antagonists, 5alpha reductase inhibitors, PDE-5 inhibitors

Question 10

Bipolar disorder

Answer 10

Mood stabilizers (eg, lithium, valproate, carbamazepine), atypical antipsychotics

Question 11

Breast cancer in postmenopausal women

Answer 11

Aromatase inhibitor (anastrozole)

Question 12

Buerger disease

Answer 12

Smoking cessation

Question 13

Bulimia nervosa

Answer 13

SSRIs

Question 14

Candida albicans

Answer 14

Topical azoles (vaginitis); nystatin, fluconazole, caspofungin (oral/esophageal); fluconazole, caspofungin, ampho B (systemic)

Question 15

Carcinoid syndrome

Answer 15

Octreotide

Question 16

Chlamydia trachomatis

Answer 16

Doxycycline (+ ceftriaxone to cover gonorrhea)

Question 17

Chronic gout

Answer 17

Xanthine oxidase inhibitors (allopurinol, febuxostat); pegloticase, probenecid

Question 18

Chronic hepatitis B or C

Answer 18

IFN-alpha (HBV and HCV); ribavirin, simeprevir, sofosbuvir (HCV)

Question 19

Chronic myelogenous leukemia

Answer 19

Imatinib

Question 20

Clostridium botulinum

Answer 20

Antitoxin

Question 21

Clostridium difficile

Answer 21

Oral metronidazole; if refractory- vancomycin

Question 22

Clostridium tetani

Answer 22

Antitoxin

Question 23

CMV

Answer 23

Ganciclovir, foscarnet, cidofovir

Question 24

Crohn disease

Answer 24

Corticosteroids, infliximab, azathioprine

Question 25

Cyptococcus neoformans

Answer 25

Fluconazole

Question 26

Cyclophosphamide-induced hemorrhagic cystitis

Answer 26

Mesna

Question 27

Diabetes insipidus

Answer 27

Desmopressin (central); hydrochlorothiazide, indomethacin, amiloride (nephrogenic)

Question 28

Diabetic ketoacidosis

Answer 28

Fluids, insulin, K+

Question 29

Drug of choice for anticoagulation during pregnancy

Answer 29

Heparin

Question 30

Enterococci

Answer 30

Vancomycin, aminopenicillins/cephalosporins

Question 31

Erectile dysfunction

Answer 31

Sildenafil, tadalafil, vardenafil

Question 32

ER + breast cancer

Answer 32

Tamoxifen

Question 33

Ethylene glycol/ methanol intoxication

Answer 33

Fomepizole (alcohol dehydrogenase inhibitor)

Question 34

H. influenzae (B)

Answer 34

Rifampin (prophylaxis)

Question 35

Generalized anxiety disorder

Answer 35

SSRIs/SNRIs (first line); buspirone (second line)

Question 36

Granulomatosis with polyangitis (Wegener)

Answer 36

Cyclophosphamide, corticosteroids

Question 37

Heparin reversal

Answer 37

Protamine sulfate

Question 38

HER2/neu + breast cancer

Answer 38

Trastuzumab

Question 39

Hyperaldosteronism

Answer 39

Spironolactone

Question 40

Hypercholesterolemia

Answer 40

Statin (1st line)

Question 41

Hypertriglyceridemia

Answer 41

Fibrate

Question 42

Immediate anticoagulation

Answer 42

Heparin

Question 43

Infertility

Answer 43

Leuprolide, GnRH (pulsatile), clomiphene

Question 44

INfluenza

Answer 44

Oseltamivir, zanamivir

Question 45

Kawasaki disease

Answer 45

IVIG, high-dose aspirin

Question 46

Legionella pneumonia

Answer 46

Macrolides

Question 47

Long-term anticoagulation

Answer 47

Warfarin, dabigatran, rivaroxaban, and apixaban

Question 48

Malaria

Answer 48

Chloroquine, metfloquine, atovaquone/proguanil (for blood schiont), primaquine (for liver hypnozoite)

Question 49

Malignant hyperthermia

Answer 49

Dantrolene

Question 50

Medical abortion

Answer 50

Mifepristone

Question 51

Migraine

Answer 51

Abortive: sumatriptan, NSAIDS; prophylaxis: propranolol, topiramate, CCBs, amitriptyline

Question 52

Multiple sclerosis

Answer 52

Disease modifying therapies (beta-interferon, natalizumab); for acute flare-ups, use IV steroids

Question 53

Mycobacterium tuberculosis

Answer 53

RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)

Question 54

Neisseria gonorrhea

Answer 54

Ceftriaxone (+ doxycycline for chlamydia)

Question 55

Neisseria meningitidis

Answer 55

Penicillin/ ceftriaxone, rifampin (prophylaxis)

Question 56

Neural tube defect prevention

Answer 56

Prenatal folate

Question 57

Osteomalacia/ rickets

Answer 57

Vit D supplementation

Question 58

Osteoporosis

Answer 58

Calcium/ vit D supplementation (prophylaxis); bisphosphonates, PTH analogs, SERMS (eg raloxifene), calcitonin, denosumab (treatment)

Question 59

Patent ductus arteriosus

Answer 59

Closure- indomethacin; Maintain patency- PGE analogs

Question 60

Pheochromocytoma

Answer 60

Alpha antagonist (phenoxybenzamine)

Question 61

Pneumocystis jirovecii

Answer 61

TMP-SMX

Question 62

Prolactinoma

Answer 62

Cabergoline/ bromocriptine

Question 63

Prostate adenocarcinoma / uterine fibroids

Answer 63

Leuprolide, GnRH (continuous)

Question 64

Prostate adenocarcinoma

Answer 64

FLutamide

Question 65

Pseudomonas aeruginosa

Answer 65

Antipseudomonal penicillins, aminoglycosides, carbapenems

Question 66

Pulmonary arterial HTN (idiopathic)

Answer 66

Sildenafil, bosentan, epoprostenol

Question 67

Rickettsia rickettsii

Answer 67

Doxycycline, chloramphenicol

Question 68

Schizophrenia (negative symptoms)

Answer 68

Atypical antipsychotics

Question 69

Schizophrenia (positive symptoms)

Answer 69

Typical and atypical antipsychotics

Question 70

SIADH

Answer 70

Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline

Question 71

Sickle cell disease

Answer 71

Hydroxyurea (increases fetal hemoglobin)

Question 72

Sporothrix schenckii

Answer 72

Itraconazole, oral potassium iodide

Question 73

Stable angina

Answer 73

Sublingual nitroglycerin

Question 74

Staph aureus

Answer 74

MSSA: nafcillin, oxacillin, dicloxacillin; MRSA: vancomycin, daptomycin, linezolid, ceftaroline

Question 75

Strep bovis

Answer 75

Penicillin prophylaxis; evaluation for colon cancer if linked to endocarditis

Question 76

Strep pneumoniae

Answer 76

Penicillin/cephalosporin (systemic infection, pneumonia); vancomycin (meningitis)

Question 77

Strep pyogenes

Answer 77

Penicillin prophylaxis

Question 78

Temporal arteritis

Answer 78

High-dose steroids

Question 79

Tonic clonic seizures

Answer 79

Levetiracetam, phenytoin, valproate, carbamazepine

Question 80

Toxoplasma gondii

Answer 80

Sulfadiazone + pyrimethamine

Question 81

Treponema pallidum

Answer 81

Penicillin

Question 82

Trichomonas vaginalis

Answer 82

Metronidazole

Question 83

Trigeminal neuralgia

Answer 83

Carbamazepine

Question 84

Ulcerative colitis

Answer 84

5-ASA preparations (eg, mesalamine), 6-mercaptopurine, infliximab, colectomy

Question 85

UTI prophylaxis

Answer 85

TMP-SMX

Question 86

Warfarin reversal

Answer 86

Fresh frozen plasma (acute), vitamin K (non-acute)