classes of reactions Flashcards
1
Q
fast receptors (milliseconds)
A
Ion channels, through binding of ligands
e.g. GABA , glutamate
2
Q
semi-fast receptors (seconds)
A
GCPR, ligand is usually neurotransmitter
e.g. (nor)adrenaline
3
Q
semi-slow receptors (minutes)
A
Kinasisreceptors, insuline-like (dimerisatie!!)
E.g. growth
4
Q
slow receptors (hours)
A
kernreceptoren,
e.g. steroidreceptors als cortisol
5
Q
agonist
A
strong effect
6
Q
partial agonist
A
small effect
7
Q
antagonist
A
no effect, blocking of receptor
8
Q
competitive antagonist
A
concurrentie –> rechtsverschuiving curve
9
Q
non-competitive antagonist
A
permanent blockage –> curve verschuift omlaag
10
Q
inverse agonist
A
has negative intrinsic activity, lowers constitutive activity of receptor
