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Autonomics > Cholinergic Receptor Inhibitor > Flashcards

Cholinergic Receptor Inhibitor Flashcards

1
Q

Atropine

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Mydriasis; cycloplegia
Side Effects: General block of muscarinic functions

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2
Q

Scopolamine (Transderm-Scop)

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Prevent or reduce motion sickness
Side Effects: General block of muscarinic functions

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3
Q

Dicyclomine (Bentyl)

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Reduce transient hypermotility
Side Effects: General block of muscarinic functions

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4
Q

Tropicamide (Mydriacyl)

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Mydriasis; cycloplegia
Side Effects: General block of muscarinic functions

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5
Q

Tolterodine (Detrol)

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Treat transient cystitis; postoperative bladder spasms; incontinence
Side Effects: General block of muscarinic functions

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6
Q

Benztropine (Cogentin)

A

Class: Tertiary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Treat manifestations of Parkinson’s disease
Side Effects: General block of muscarinic functions

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7
Q

Ipratropium (Atrovent)

A

Class: Quarternary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Bronchodilation in asthma or COPD
Side Effects: General block of muscarinic functions

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8
Q

Tiotropium (Spiriva)

A

Class: Quarternary amine antimuscarinic
Mechanism: Blocks muscarinic receptors
Therapeutics: Bronchodilation in asthma or COPD
Side Effects: General block of muscarinic functions

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9
Q

Hexamethonium (Methium)

A

Class: Ganglionic blocker
Mechanism: Blocks ganglionic (Nn) receptor
Therapeutics: Hypertensive crisis; “Bloodless” field surgery

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10
Q

Succinylcholine (Anectine)

A

Class: Depolarizing blocker
Mechanism: Overstimulation of nicotinic receptor, leading to desensitization of muscle unit to further ACh stimulation
Therapeutics: Brief procedures (e.g., tracheal intubation, reset dislocated joints)
Side Effects: Respiratory paralysis; disturbance of autonomic function

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11
Q

Tubocurarine (Curare)

A

Class: Nondepolarizing blocker
Mechanism: Blocks nicotinic (Nm) receptor
Therapeutics: Muscle relaxant for surgery w/o deep anesthesia
Side Effects: Respiratory paralysis; disturbance of autonomic function

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12
Q

Mivacurium (Mivacron)

A

Class: Nondepolarizing blocker
Mechanism: Blocks nicotinic (Nm) receptor
Therapeutics: Muscle relaxant for surgery w/o deep anesthesia
Side Effects: Respiratory paralysis; disturbance of autonomic function

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13
Q

Botulinum toxin A (Botox)

A

Class: Local paralytic
Mechanism: Blocks vesicle fusion and ACh release on presynaptic terminal by degrading SNAP-25
Therapeutics: Reduce frown lines and wrinkles; achalasia; strabismus; oromandibular dystonia

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Autonomics (10 decks)

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