Cholangiocarcinoma Flashcards
1
Q
What are risk factors for cholangiocarcinoma
A
Primary sclerosing cholangitis
Fibropolycystic liver disease (choledochal cysts)
Parasitic infection with liver flukes (SE Asia)
Hepatolithiasis
Familial syndroems - Lynch, multiple biliary papillomatosis
Chronic liver disease and viral hepatitis
2
Q
What are the classification groups of cholangiocarcinoma?
A
Intrahepatic (10%)
Perihilar (50%)
Extrahepatic (40%)
3
Q
What tests are helpful in diagnosis of cholangiocarcinoma
A
Tumour markers - ca19.9, CEA, AFP USS, CT abdo MRCP ERCP/EUS PET scan laparoscopy
4
Q
What are the management strategies for cholangiocarcinoma?
A
Resectable - surgery followed by adjuvant chemo-radiation
Unresectable - palliative chemotherapy with cisplatin/gemcitabine
