Chemotherapies Flashcards
Cisplatin
Platinol
Alkylating Agent / Non-Specific
HLD, increased risk of LT cardiovascular issues, renal toxicity, SIADH, increase renal excretion of carnitine.
Selenium to protect against potential AKI
Requires additional hydration; monitor renal function and electrolytes (Mg, Potassium)
Carboplatin
Paraplatin
Alkylating Agent / Non-Specific
Renal Toxicity
Selenium to protest against AKI
Oxaliplatin
Eloxatin
Alkylating Agent / Non-Specific
Monitor Ca, Mg Cold sensitivity (phayngolaryngeal dysethesia)
Cytoxan
Cyclophosphamide
Alkylating Agent / Non-Specific
Vitamin D deficiency
Vigorous oral hydrate
Mesna given with high dose to prevent bladder inflammation
Vincristine
Oncovin
Vinca Alkaloids / CC Specific
Peripheral Neuropathy + Severe constipation
Navelbine
Vinorelbine
Vinca Alkaloids / CC Specific
Elevated LFTs. N/V/C
Gemcitabine
Gemzar
Antimetablite / CC Specific
N/V, flu-like symptoms
Curcumin (+fatty foods)
5FU
Fluourouracil
Antimetablite / CC Specific
Mucositis, diarrhea
Thiamine def + cardiac failure possible
Xeloda
Capcetabine
Antimetablite / CC Specific
Hand/Food syndrome (Vitamin B6)
Methotrexate
MTX
Antimetablite / CC Specific
Hepatic toxicity, GI ulceration @ high levels
Cytarabine
ARA-C
Antimetablite / CC Specific
toxic to kidneys + liver
Avastain
Bevacizumab
Biotherapy / Immunotherapy / Angiogenesis Inhibitor
GI perf, HTN, CHF, thrombocytopenia.
Met CRC
Cetuximab
Erbitux
Biotherapy / Immunotherapy /Monoclonal Antibody
wt loss, mucositis, LOA.
Monitor Mg, Ca
Cardiac/respiratory distress
Herceptin
Trastuzumab
Biotherapy / Immunotherapy / Monoclonal Antibody
Flu like symptoms
Rituxan
Rituximab
Biotherapy / Immunotherapy / Monoclonal Antibody
TLS.
lymphoma +CLL
