Chapter 9 Tables Flashcards

1
Q

Ozone effects on healthy people

A

lung inflammation and decreased lung function

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2
Q

Ozone on athletes, outdoor workers

A

decreased exercise capacity

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3
Q

Ozone on asthmatics

A

increased hospitalization

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4
Q

NO2 on healthy adults

A

increased air reactivity

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5
Q

NO2 on athmatics

A

decreased lung function

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6
Q

NO2 on children

A

increased respiratory infection

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7
Q

SO2 on healthy people

A

increased respiratory symptoms

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8
Q

SO2 on people with chronic lung disease

A

increased mortality

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9
Q

SO2 on asthmatics

A

increased hospitalization and decreased lung function

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10
Q

Acid aerosols on healthy people

A

altered mucociliary clearance

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11
Q

Acid aerosols on children

A

increased respiratory infections

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12
Q

Acid aerosols on asthmatics

A

decreased lung function

increased hospitalization

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13
Q

Paticulates effect on children

A

increased respiratory infections

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14
Q

Particulates effect on people with lung or heart disease

A

decreased lung function

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15
Q

Particulates effect on asthmatics

A

excess mortality and increased attack

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16
Q

What occupational exposures can cause heart disease

A

CO, lead, solvents, cobalt, cadmium

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17
Q

What occupational exposures can cause nasal cancer

A

isopropyl alcohol, wood dust

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18
Q

What occupational exposures can cause lung cancer

A

radon, asbestos, silica, aresnic

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19
Q

What occupational exposures can cause chronic obstructive lung disease?

A

cadmium

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20
Q

What occupational exposures can cause hypersensitivity

A

beryllium

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21
Q

What occupational exposures can cause irritation of respiratory tract

A

ammonia, formaldehyde

22
Q

What occupational exposures can cause fibrosis of respiratory tract

A

asbestos

23
Q

What occupational exposures can cause renal toxicity

A

mercury, lead

24
Q

What occupational exposures can cause male infertility

A

lead, cadmium

25
Q

What occupational exposures can cause female infertility and still birth

A

lead and mercury

26
Q

What occupational exposures can cause teratogenesis

A

mercury

27
Q

What occupational exposures can cause leukemia

A

benzene

28
Q

What occupational exposures can cause skin cancer

A

UV radiation

29
Q

What occupational exposures can cause liver angiosarcoma

A

vinyl chloride

30
Q

Cancers from polycyclic hydrocarbon

A

lung and bladder cancer

31
Q

What can nonpesticide organochlorines cause?

A

skin disorders; chloracne

32
Q

What is chloracne

A

combination of folliculitis and dermatosis

characterized by acne, cyst formation, hyperpigmentation on face and ears

33
Q

What are the nonpesticcide organochlories?

A

PCB (polychlorinated biphenyls) and dixon

34
Q

What does inhalation of mineral dust cause

A

pneumoconioses

35
Q

What is pneumoconioses?

A

chronic, nonneoplastic lung disease

36
Q

Most common mineral dusts (4)

A

coal dust, silica, asbestos, beryllium

37
Q

Carcinogenic elements in tobacco (4)

A

tar, polycyclic aromatic hydrocarbons, benzoapyrene, and nitrosamine

38
Q

Effect of nicotine on body from tobacco

A

not direct cause of tobacco-related disease but is strongly addictive
stimulates catecholamine release and sympathetic effects

39
Q

Effect of formaldehyde and nitrogen oxides in tobacco

A

toxicity to cilia and mucosal irritation

40
Q

How can passive smoke inhalation be estimated in nonsmokers?

A

cotinine which is a metabolite of nicotine

41
Q

What causes analgesic nephropathy?

A

aspirin toxicity- can cause tubulointestinal nephritis and renal papillary necrosis

42
Q

Opiod narcotic target and example

A

Mu opiod receptor

heroine and oxycodine

43
Q

Sedative hypnotic target and example

A

GABA receptor agonist

ethanol and barbiturates

44
Q

Psychomotor stimulants target and example

A

dopamine transporter antagonist- cocaine

serotonin receptor toxicity- amphetamines and MDMA (ecstasy)

45
Q

Cannabinoids target and example

A

CB1 receptor agonist

marijuana and hashish

46
Q

What occurs in the first hours of acute radiation syndrome?

A

lymphopenia

47
Q

What occurs in the first day of acute radiation syndrome?

A

neutropenia

48
Q

What occurs in the first week of acute radiation syndrome?

A

thrombocytopenia

49
Q

What occurs in 2-3 weeks of acute radiation syndrome?

A

anemia

50
Q

When does fibrosis occur after radiation? and where?

A

weeks to months after radiation

lungs and salivary glands

51
Q

Function of POMC and CART on appetite

A

stimulate TSH and CRH to increase metabolic rate