Chapter 75 Primary Wound Closure Flashcards
NSAIDs effect on incisional healing
In mice treated with a COX-2 inhibitor, no effect on wound healing was noted for 28 days.
How many suture throws to start continuous pattern with PDS
Minimum 5 throws at the start or end of a simple continuous
Dog vs cat wound healing - which forms granulation tissue earlier and how long to form complete granulation tissue bed
dogs - ~7 days
Cats - ~19 days
How is cutaneous blood perfusion in cats compared to dogs
Cats have lower cutaneous perfusion one week after surgery
How do cats heal their wounds in comparison to dogs
Cats heal by contraction along wound edges and dogs heal by central “pull” of fibroblasts and epithelialization.
Skin is how strong by what time points through healing
5-10% as strong as unwounded skin 14 days PO
25% 3-4 weeks PO
70-80% of ultimate strength at several months PO
80% of normal strength 1 year PO
Whats the breaking strength of wounds in dogs vs cats 7 days post op
0.4kg at 7 days in cats vs 0.8kg in dogs
Where are hair follicles located in the skin
Hair follicles are present in the dermis and the upper part of the hypodermis
What direction do the direct cutaneous vessels run and what do they supply?
Direct cutaneous vessels in dogs and cats at the level of the cutaneous trunci muscle run parallel to the overlying skin and supply the subdermal plexus
Do NSAIDs have any clinical effect on wound healing
In mice treated with a COX-2 inhibitor, no effect on wound healing was noted for 28 days.
