Chapter 2, Conception, Heredity Flashcards

1
Q

Polygenic

A

human features as a result of many genes

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2
Q

Multifactorial:

A

human features are a result of many factors, both genetic and environmental

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3
Q

Epigenetic Framework:

A

bidirectional interplay between nature and nurture; suggests that environment can affect the expression of genes just as genetic predispositions can impact a person’s potentials

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4
Q

Passive Genotype Environment Correlation:

A

occurs when children passively inherit genes and the environments their families naturally provide (for example, athleticism: inherited genes that are already healthy, plus being raised in an environment where working out/sports is commonplace) climbers

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5
Q

Evocative Genotype Environment Correlation:

A

refers to how the social environment reacts to individuals based on their inherited characteristics (EXAMPLE: whether someone is shy or outgoing affects how others treat them: THEY EVOKE THIS RESPONSE FROM THE ENVIRONMENT), social anxiety

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6
Q

Active Genotype Environment Correlation:

A

occurs when individuals seek out environments that support their genetic tendencies “NICHE PICKING” (EXAMPLE: children who are naturally musically inclined seek out music instruction)

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7
Q

Adoption studies and likelihood of developing psychopathology

A

RESULTS 1: children whose biological parents exhibited psychopathology exhibited fewer behavioral problems when their adoptive parents used more structured parenting than unstructured
RESULTS 2: elevated psychopathology in adoptive parents increased the risk for the children’s development of behavioral problems BUT ONLY WHEN THE BIOLOGICAL PARENTS’ PSYCHOPATHOLOGY WAS HIGH
CONCLUSION: results show how environmental effects on behaviur differ BASED ON GENOTYPE, especially stressful environments combined with generally at-risk children

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8
Q

Genes:

A

recipes for making proteins, while proteins influence the structure and functions of cells; located on the chromosome

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9
Q

Mitosis:

A

cell’s nucleus making an exact copy of all the chromosomes and splitting into two new cells; MOST CELLS OF THE BODY ARE MADE THIS WAY AFTER CONCEPTION

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10
Q

Meoisis:

A

forms the cells used in sexual production like sperm or ova (gametes); the gamete’s chromsomes duplicate and then divide twice resulting in four cells containing only half the genetic material of the original gamete (THUS EACH SPERM AND EGG POSSESSES ONLY 23 CHROMOSOMES AND COMBINES TO PRODUCE THE NORMAL 46)

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11
Q

Autosomes:

A

of the 23 pairs of chromosomes created at conception, 22 pairs are at similar length

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12
Q

Sex Chromosomes:

A

differ in length; XY male XX female

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13
Q

Homozygous vs heterozygous/ allelles

A

Homozygous: when both genes inherited from the mother and father (both pairs) are the same = WE WILL DISPLAY THAT CHARACTERISTIC
If we receive a different version of the gene from each parent: HETEROZYGOUS, THE DOMINANT ONE WILL WIN
Recessive genes can only express themselves when paired with a similar version gene (alleles)

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14
Q

Huntington’s Disease;

A

Most genetic disorders are linked to the dominant gene, but most of these are not serious
dominant gene linked disorder that affects the nervous system and is fatal, but does not appear until midlife

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15
Q

Why are recessive gene disorders more likely to be fatal?

A

Recessive gene disorders: cystic fibrosis and sickle-cell anemia, less common but more fatal because they are less likely to be detected

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16
Q

Why are men at greater risk for sex-linked disorders and in what situation are females equally at risk?

A

Men are at greater risk for sex-linked disorders due to a recessive gene such as hemophilia, color blindness, and baldness
For females to be affected by recessive genetic defects, they need to inherit the recessive gene on BOTH X CHROMOSOMES
^^IF THE DEFECTIVE GENE IS DOMINANT, FEMALES ARE EQUALLY AT RISK THOUGH

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17
Q

Put all genetic disorders in flashcards?

A
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18
Q

Chromosomal Abnormality and causes

A

occurs when a child inherits too many or too few chromosomes: MOST COMMON CAUSE IS THE AGE OF THE MOTHER; as the mother ages, the ovum is more likely to suffer abnormalities due to longer term exposure to environmental factors

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19
Q

Sex Linked Chromosomal Disorders

A

When an abnormality occurs on the 23rd pair; when person has more or less than two sex chromosomes

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20
Q

Zygote vs blastocyte

A

Zygote: cell containing the combined genetic info from both parents
Blastocyte: after 5 days of mitosis, 100 cells

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21
Q

Why is mitosis fragile?

A

Mitosis is fragile and fewer than one half of all zygotes survive beyond the first two weeks; egg and sperm didnt join properly, too little or damaged genetic material, zygote doesn’t replicate, blastocyte doesn’t implant into uterine wall

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22
Q

When does the embryonic period start and what kind of developments begin?

A

Embryo, Week 3 Gestational Age (5 Weeks Maternal)
Basically a worm like tube
Starting 3rd week, the blastocyst has implanted into the uterine wall
Placenta separates baby’s blood from mother’s; acts as a filter, nourishes fetus
Placenta takes urine from fetus out and filters out hazardous chemicals
Our common ancestor is a fish= why we have tails/gills
Cephalocaudal Development: head to tail development, structures nearest head develop first
Proximodistal Development: midline outward, structures nearest torso develop first

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23
Q

When does the fetal organism begin responding to touch?

A

20% of organisms fail during the embryonic period, approximately 1 inch and can respond to touch

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24
Q

Fetal Period/ first chance of survival outside womb

A

Referred to as fetus
Third month fetus has all body parts including genitalia
24 weeks; pain can be felt at this stage

25
Q

Mono vs dizygotic twins

A

Mono: identical; RESULTS FROM A FERTILIZED EGG SPLITTING APART IN THE FIRST TWO WEEKS OF DEVELOPMENT, creates two separate but identical offspring
Dizygotic; fraternal, share same amount of genetic material as any two siblings

26
Q

Teratogens and important factors in exposure that matter

A

Teratogens; environmental factors that can contribute to birth defects
Timing of exposure during which period of development, amount of exposure, number of teratogens introduced, genetic makeup, and being male or female (MALES ARE MORE LIKELY TO EXPERIENCE DAMAGE TO TERATOGENS THAN FEMALES, because of the Y chromosome)

27
Q

Time periods that teratogens are introduced and the impacts

A

If teratogens are introduced during week 1 and 2: prenatal death often results
Teratogens introduced week 3–9: major morphological abnormalities
Teratogens introduced week 9—38: functional defects and minor morphological abnormalities

28
Q

Trisomy 21, Down Syndrome:

A

third chromosome on 21st pair (ALMOST always except for this case a third would result in death)

29
Q

Physical, metabolic, infections, drug and chemical, herb teratogens

A

Physical Teratogens: infections, hot tubs, saunas: raise the mother’s body temp to 120 or higher, associated with neural tube defects, spontaneous abortions, and cardiovascular abnormalities
Metabolic: abnormalities in the chemical process of producing energy from good, and thereby affect the development and function of the body (MALNOURISHMENT, DIABETES, THYROID DISORDERS)
Infections: rubella virus, herpes simplex virus, and syphilis can cause congenital abnormalities in fetuses
DRugs and Chemicals: radiation, heavy metals, insectisdies and herbicides, prescription and over counter drugs, illicit and recreational drugs, cigarettes, nicotine, caffeine and even some vitamins
Some herbs may also impact pregnancy

30
Q

Caffeine and pregnancy

A

Linked to miscarriage and preterm birth

30
Q

know all impacts of every drug as teratogens?

A
31
Q

Risks for Mother’s Over 35

A

Fertility problems
High blood pressure
Diabetes
Miscarriages
Placenta Previa
Need c section
Premature birth
Stillbirth
Baby with genetic defect or other birth defects
However, older women statistically are more stable, demonstrate stronger family focus, have more money, women who delay having children actually live longer, for every year a woman delays motherhood she makes 9% more in lifetime earnings

32
Q

Teen pregnancy issues

A

Greater risk for complications like anemia and high blood pressure
Low birthweight
Bleeding in brain, breathing problems, intestinal defects, and higher likelihood of dying occurs in premature infants
Teens may also engage in negative behaviors including eating unhealthy food, smoking, drinking alcohol, and taking drugs

33
Q

Gestational Diabetes

A

Can cause premature birth, stillbirth, breathing problem at birth, jaundice, or low blood sugar in fetus
Preeclampsia: high blood pressure and signs that the liver and kidneys may not be working proper;ly; MAY BE CAUSED BY GESTATIONAL DIABETES

34
Q

Hypertension and pregnancy

A

Pressure against wall of the arteries becomes too high
Gestational Hypertension: occurs only during pregnancy and goes away after birth
High blood pressure can cause premature birth and low birth weights, placental abruption, and preeclampsia

35
Q

Rh Disease and pregnancy

A

Most people are Rh positive, meaning they have this protein
Mothers without it are at risk of having a baby with a form of anemia called Rh Disease
A father who is Rh positive and a mother who is Rh negative can conceive a baby who is Rh positive: the problem with this is that some of the fetus’ blood cells may get into the mother’s bloodstream and her immune system tries to fight the new rH factor and destroy the blood cells of the developing fetus (subsequent pregnancies are at even greater risk as the mother’s body now continues to produce antibodies to the Rh factor across her lifetime)

36
Q

Risks for Offspring of men over 40 and why

A

t higher risk for miscarriage, autism, birth defects, achondroplasia (bone growth disorder) and schizophrenia: DUE TO THE ACCUMULATED CHROMOSOMAL ABERRATIONS AND MUTATIONS DURING THE MATURATION OF SPERM CELLS IN OLDER MEN

37
Q

Amniocentesis:

A

procedure in which a needle is used to withdraw a small amount of amniotic fluid and cells from the sac surrounding the fetus (MAY CAUSE MISCARRIAGE)

38
Q

Chorionic Villus Sampling:

A

procedure in which a small sample of cells is taken from the placenta and tested (MAY CAUSE MISCARRIAGE)

39
Q

How do fathers not dictate the sex of the child like previously thought?

A

Dads do NOT dictate the sex like previously thought (thought that it depended whether he donated X or Y): a lot of mothers have selective miscarriages based on the sex of the baby; some women can’t carry boys or girls and their body will self-abort: means that both parents can determine the sex

40
Q

Why is hermaphrodite no longer used as a term for intersex individuals

A

Neither male nor female
Hermaphrodite was the previous word for it, because it assumed both gonads: this is not right, bc it would say that a human could have sperm and ovum and could reproduce healthily with both
Intersex means that external genitalia is ambiguous: physical not psychological

41
Q

Turner’s Syndrome

A

`Only one sex chromosome: X )(most likely came from egg and sperm didn’t provide sex chromosome)
Tend to be assigned female at birth
At puberty, don’t develop typically like people with XX chromosomes
Phenotypic expressions: broader chest, shorter, wider neck
Might not get period whatsoever and do not ovulate, breasts don’t fully develop
This does exist on a spectrum and symptoms are not universally
IVF MAY BE SUCCESSFUL WITH TURNER’S SYNDROME BUT IT IS DIFFICULT due to lack of ovary maturity
Half of ovaries wouldn’t develop at all because they wouldn’t have an X in them = a lot of infertility issues

42
Q

Klinefelter’s Syndrome

A

Three sex chromosomes: XXY
Usually assigned male at birth
Some develop as male and are fertile
Some individuals have such ow sperm count, infertility, breast development, less body hair, fat distribution that looks more female
Some of these individuals identify as non-binary, trans, or something else on the spectrum

43
Q

Congenital Adrenal Hyperplasia:

A

has XX chromosomes, but absorb extra amounts of testosterone in the womb
Tend to be more masculine
Congenital means from the start
Hyperplasia means hyper absorbent

44
Q

Androgen Insensitivity Syndrome, XY

A

Individuals who have a Y chromosome that would be expected to produce testosterone but they don’t and their body can’t absorb it
More feminine, some may produce some testosterone
No uterus and no ability to get pregnant, no ovaries
Have internal testes that have not descended
Usually don’t find out their not a “woman” like this until trying to have a family

45
Q

Other Chromosomal Abnormalities

A

XYY: tend to have higher testosterone “superman” taller than average increased risk of learning problems more acne
XXX: no phenotypic differences but seizures, learn8ng disabilties, kidney problems, taller 5han averafe
XXXX: no changes either

46
Q

How is gestational and maternal time counted differently in pregnancy?

A

Gestational: time of actual conception
Maternal time: first day of last period

47
Q

Steps of fertilization/implantation cramps

A

Fertilization occurs when a sperm breaks through to an egg
24-30 hrs after sperm enters: Y chromosomes combine
36 hours: zygote divides into 2 cells
48 hours: 4 cells
3 days after fertilization: 16-32 cells
4 days–Blastocyte of 100 cells (NO SPECIALIZATION YET)
5 days: zygote is getting to uterus (IMPLANTATION)
6-7 Days: attaches to uterine wall
12-14 days: implanted on uterine wall (GET A SUCCESSFUL POSITIVE PREGNANCY TEST AT THIS POINT)
Connects with blood vessels, signals parent’s brain and connects the bloodstreams, triggers hormones for physiological symptoms

48
Q

Germ Disc and three layers

A

Ectoderm: outer layer (specialize into skin, hair, and peripheral nervous system
Mesoderm: middle layer (muscles/bones) ‘
Endoderm: inner layer (central nervous system, digestive tract)
(GASTRULATION MAKES THIS BECOME A THREE DIMENSIONAL TUBE/PINCHING FORM)

49
Q

How does vision begin in the womb?

A

Get photoreceptive eyes at this age (simple little cells)

50
Q

Week 5 Gestational Age

A

Kidneys
Mouth and tongue

51
Q

Week 6

A

Face, lips, nose, eyelids
Limbs starting to d

52
Q

Week 7

A

Neurogenesis FIRST BRAIN CELLS
We don’t know if there’s any pain receptors
Head is getting very big: grape size

53
Q

Week 8 (RISKY STAGE)

A

Knees, elbows, ankles
Miscarriages will happen at this point if there is a problem i/n the genetic code: THIS IS WHEN THE CODE BREAKS DOWN

54
Q

3rd Month, sex characteristics and males being behind females

A

Primary sex characteristics
Everyone was female: STARTS OFF WITH WHAT WILL BE VULVA AND VAGINA: if there is enough testosterone, then ovaries become testes and vaginal tube will become penis
This is when we figure out the sex of the baby
If male babies are born premature, they are at more risk because it takes them longer to make a penis and therefore delays their respiratory systems and other systems
Until age 6, males are behind females because of this ^^ impacts developmental impacts (language development)
First few years of elementary school boys tend to get more sick because of less developed immunity

55
Q

4th Month

A

Parent is most likely to feel fetus move “the quickening”
Miscarriage is much less risky

56
Q

5th Month

A

Lanugo: downy hair all over the body: fetuses don’t have enough body fat to regulate temperature and need this
Vernix: white coating that is water resilient, keeps the “finger prune” effect from happening (if they’re born early they will still have this on)

57
Q

cystic fibrosis

A

body overproduces mucus which often lesds to breathing problems recessive disorder

58
Q

Oocyte

A

When egg is just released but has not been fertilized yet