Chapter 2:Cellular Injury, Adaptation and Maladaptation changess Flashcards
atrophy
cells revert to smaller size
Causes of atrophy
disuse, loss of hormonal stim, decreased blood flow(ischemia), lack of nerve stimulation, inadequate nutrition and aging
Hypertrophy
increase in cell size, each cell becomes larger
physiological hypertrophy
enlargement is adequately perfused and supplied with blood flow, oxygen and nutrients
pathological hypertrophy
increase in size without increase in supportive structures
hyperplasia
increase in number of cells, ex:pregnancy
Metaplasia
replacement of one cell type by another cell type; result of genetic reprogramming
Dysplasia
deranged cellular growth within a specific tissue
Neoplasia
New growth and refers to disorganized, uncoordinated, uncontrolled proliferative cell growth that is cancerous
Dysfunction of Na/K pump
unable to produce ATP, cellular swelling
apoptosis
programmed cellular death without inflammation
hypoxic cell injury
oxygen deprivation
hypoxemia
low oxygen in the blood
necrosis
cells die when stressor or insults overwhelm ability to survive. irreversible, autolysis occurs
infarction
ischemic necrosis