Chapter 16: The molecular basic of inheritance Flashcards
What did Watson and Crick do
Create first model of DNA
What does each nucleotide include
A sugar, phosphate and nitrogenous base
What type of sugar is DNA and sugar for RNA
Deoxyribose for DNA and ribose for RNA
How many H-bonds between A and T
2 H-bonds
How many H-bonds between G and C
3 H-bonds
Structure of DNA
- Antiparallel
- Base connects bdy H-bond
- Double Helix.
What is semi-conservative model for DNA replication
Parental molecule seperates and one new and one old strand form together to make new two models
Where does replication begin at
- At particular sites on chromosomes called origins of replication
How many origins eukaryotes have
Hundreds or thousands
How many origins prokaryote have
One
What type of chromosome does eukaryote has
Linear
What type of chromosome does prokaryote has
Circular
What type of enzymes in DNA replication
- Helicase
- Primase
- DNA polymerase
- Topoisomerase
- Single-stranded protein
- Ligase
Does mismatch repair or nucleotide excision repair fix bigger problem
- Nucleotide excision repair
DNA + protein =?
Chromatin
DNA + Histones =?
Nucleosomes
What are histones
Proteins responsible for the first level of packing in chromatin
