Chapter 10: Alterations in Immune Function

Question 1

what are two categories of inappropriate immune response

Answer 1

excessive: over-or-high functioning
deficient: inadequate functioning

Question 2

true or false: autoimmune disorders range from organ-specific to organ nonspecific diseases

Answer 2

true

Question 3

true or false: gender is an issue where females are at a higher risk of developing autoimmune disease than males

Answer 3

true

Question 4

is hypersensitivity a normal immune response

Answer 4

yes, normal immune response is either inappropriately triggered, excessive, and produces undesirable effects on the body

Question 5

hypersensitivity is divided into

Answer 5

type I, type II, type III, type IV

Question 6

what are hypersensitivity types mediated by

Answer 6

type I, II, III= antibodies

type IV= T cells

Question 7

true or false: type I hypersensitivity is known as immediate hypersensitivity, so reaction occurs 15 to 30 minutes after exposure

Answer 7

true

Question 8

what are the immunoglobulins that mediate type II hypersensitivity

Answer 8

IgG or IgM

Question 9

true or false: type II hypersensitivity is also known as tissue specific

Answer 9

true

Question 10

what is an example of type II hypersensitivity

Answer 10

transfusion reaction

Question 11

true or false: type III hypersensitivity results from failure of immune system to remove antigen-antibody immune complexes (IC’s)

Answer 11

true

Question 12

is type IV hypersensitivity is defined as rapid or delayed response

Answer 12

delayed

Question 13

persistent asthma is an example of which type IV hypersensitivity

Answer 13

IVb, where T cells produce and release inflammatory cytokines and initiate eosinophil involvement, and release in response to severe airway inflamed and asthma symptoms

Question 14

what are primary disorders under deficient immune response

Answer 14

B cell disorders, T cell disorders, combined B & T cell disorders, which can be congenital or acquired

Question 15

true or false: selective IgA deficiency is an example of T cell disorder

Answer 15

false: B cell disorder

Question 16

the deletion of which chromosome causes DiGeorge syndrome

Answer 16

deletion of a section of chromosome 22 (22q11)

Question 17

Wiskott-Aldrich syndrome is an X linked immunodeficiency disorder that affects …

Answer 17

both T cells & B cells

Question 18

an acquired primary immunodeficiency, such as HIV/ AIDS causes a decrease in the number of what

Answer 18

CD4+ ( T helper cells)

Question 19

true or false: AIDS causes a T cell count of below 250/ ul

Answer 19

false: T cell count of below 200/ul