CHAPTER 01 - WOUNDS

Question 1

what are the phases of wound healing?

Answer 1

• substrate (inflammatory / lag / exudative)
• proliferative (collagen and fibroblastic)
• remodeling (maturation)

Question 2

what are the characteristics of the substrate phase of wound healing?

Answer 2

• s/sx of inflammation
• physiology of inflammation
• removal of clot / debris / bacteria

Question 3

how long does the substrate phase of wound healing last? in primary intention healing? secondary / tertiary intention healing?

Answer 3

• 1 - 4 days
• primary intention: 4 days
• secondary intention: until wound is closed

Question 4

how long does the proliferative phase of wound healing last?

Answer 4

4 - 42 days

Question 5

what are the characteristics of the proliferative phase of wound healing?

Answer 5

• synthesis of collagen tissue from fibroblasts
• increased rate of collagen synthesis for 42-60 days
• rapid gain of tensile strength in the wound

Question 6

how long does the remodeling phase of wound healing last?

Answer 6

from 3 weeks onward, up to 9 months in adults

Question 7

what are the characteristics of the remodeling phase of wound healing?

Answer 7

• maturation by intermolecular cross linking of collagen leads to flattening of scar
• dynamic, ongoing

Question 8

what phase of wound healing involves the synthesis of collagen tissue from fibroblasts?

Answer 8

proliferative

Question 9

what phase of wound healing involves removal of clot / debris / bacteria?

Answer 9

substrate

Question 10

what phase of wound healing involves intermolecular cross linking of collagen?

Answer 10

remodeling

Question 11

what phase of wound healing is dynamic and ongoing?

Answer 11

remodeling

Question 12

what phase of wound healing involves an increased rate of collagen synthesis?

Answer 12

proliferative

Question 13

what phase of wound healing involves a rapid gain of tensile strength in the wound?

Answer 13

proliferative

Question 14

what ultimately determines the final result of a scar?

Answer 14

how well the dermis was approximated

Question 15

what are the different types of wound closure?

Answer 15

• primary
• secondary / spontaneous
• tertiary

Question 16

in secondary intention healing the wound is maintained in the __________ phase until the wound is closed

Answer 16

inflammatory

Question 17

in secondary intention healing the wound is maintained in the inflammatory phase until:

Answer 17

the wound is closed

Question 18

spontaneous wound closure depends on what two factors?

Answer 18

• contraction

- epithelialization

Question 19

contraction of a wound is the result of what process?

Answer 19

centripetal force in wound margin probably provided by myofibroblasts

Question 20

epithelialization proceeds from wound margins toward the center at ___ mm / day

Answer 20

1 mm / day