Ch 48: Musculoskeletal Systems Flashcards

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0
Q

Vertebrate muscle for voluntary movement…

A

Skeletal

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1
Q

Three types of vertebrate muscle…

A
  • skeletal
  • cardiac
  • smooth
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2
Q

Vertebrate muscle for heart beat…

A

Cardiac

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3
Q

Vertebrate muscle for involuntary movement of internal organs

A

Smooth

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4
Q

Skeletal muscle cells are called…

-large and multinucleate

A

Muscle fibers

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5
Q

Muscle fibers form from fusion of embryonic…

A

Myoblasts

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6
Q

One muscle consists of many muscle fibers bundled together by…

A

Connective tissue

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7
Q

2 contractile proteins:

A
  • actin

- myosin

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8
Q

Thin filaments

A

Actin

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9
Q

Thick filaments

A

Myosin

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10
Q
  • each muscle finer has several…

- bundles if actin and myosin filament

A

Myofibrils

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11
Q

Each myofibril consists of…

  • repeating units of overlapping actin and myosin fibers
  • create distinct banding pattern
A

Sarcomeres

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12
Q

Each sarcomere is bounded by…

-anchor actin

A

Z lines

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13
Q

Parts of sarcomere

A
  • Z lines
  • A band
  • H zone and I band
  • M band
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14
Q
  • Center of sarcomere

- contains all myosin

A

A band

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15
Q
  • part f sarcomere
  • no overlap of actin and myosin
  • (light)
A

H zone and I band

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16
Q
  • part of sarcomere
  • located within H zone
  • contains proteins that help hold myosin filaments in regular arrangement
  • (dark)
A

M band

17
Q
  • Largest protein in the body

- runs the full length if the sarcomere (from Z line to Z line)

A

Titin

18
Q

Bundles of myosin filaments are held in the center of the sarcomeres by…

A

Titin

19
Q

When muscle contracts, sarcomeres ….. and band pattern …..

A

Shorten, changes

20
Q

…… of muscle contraction depends in structure if actin and myosin molecules

A

Sliding filament model

21
Q

Myosin molecule has ……. coiled together, engine in a globular head

A

2 polypeptide chains

22
Q

Myosin moodle clue has 2 polypeptide chains coiled together, ending in a …..

A

Globular head

23
Q

Myosin filament is many molecules in ….

A

Parallel

24
Q

Actin filament is ……. in a long, twisted molecule

A

Actin monomers

25
Q

Twists around actin

A

Tropomyosin

26
Q

Attached at intervals to tropomyosin

A

Troponin

27
Q

….. can bind specific sites on actin molecules to form cross bridges

A

Myosin heads

28
Q

Myosin changes conformation causing actin filament to ……

A

Slide 5-10 nm

29
Q

Muscle membranes are ….

-membranes can conduct AP

A

Excitable

30
Q

Muscle contraction is initiated by AP from a motor neuron at the ……

A

Neuromuscular junction

31
Q

A —– all the muscle fibers activated by one motor neuron

A

Motor unit

32
Q

Actin-myosin interactions are controlled by —–

A

Ca2+

33
Q

3 subunits of Troponin:

A
  1. Binds to actin
  2. Binds to tropomyosin
  3. Binds to Ca2+
34
Q

To increase strength of muscle contraction:

A
  1. Increase rate of firing of motor neuron

2. Recruit more motor neurons to fire (more motor units activated)

35
Q

—– descend into sarcoplasm

A

T tubules

36
Q

Muscle fiber cytoplasm

A

Sarcoplasm

37
Q

T tubules descend into —–

A

Sarcoplasm

38
Q

T tubules run close to the —-

- closed compartment that surrounds every myofibril

A

Sarcoplasmic reticulum

39
Q

“Smooth ER of muscle”

A

Sarcoplasmic reticulum

40
Q

Sarcoplasmic reticulum has —– pumps

A

Ca2+

41
Q

At rest Ca2+ concentration is higher in —– and lower in —–

A

Sarcoplasmic reticulum, sarcoplasm