Ch 19: Blood Flashcards
Thrombocyte
Blood clot that stationary
Embolus
Traveling blood clot
White blood (greatest amount to least)
-Neutrophils
-Lymphocytes
-Monocytes
-eosinophils
-Basophils
Megakaryocyte
Mature, erythrocytes
-Last 128 days (4mo) what is
What are megakaryocytes when broken into pieces?
Platelets
What are the three components that form elements?
Red blood cells, white blood cells, platelets
What are the 4 proteins in plasma?
Globulin
-Immuno globulin
-Albumin: most abundant protein in plasma
-Fibrinogen
Fibrinogen
Thread like structure to stabilize blood clots
-platelet plug
Fibrin
Active form of fibrinogen
What is the shape of a red blood cell?
Biconcave shape
How many types of leukocytes are there?
Five types
Neutrophil
Most abundant
-large, 3-5 lobes
Eosinophil
Large, pink/red
Basophil
Least abundant
-Large, blue/black
What are agranulocytes
Monocyte: immunity, kidney shape
Lymphocyte: large, dark
Even though lymphocytes are small, are they still bigger than red blood cells?
Yes
Monocyte macrophage system
- Chemitaxis: Moved to infected tissue.
- Margination: Move towards endothelium.
- Diapedsis: Cells move through cells to capillaries.
Events preventing excessive blood loss
- Vascular spasm: vasoconstriction of damage, blood vessels.
- Platelet plug formation.
- Coagulation/blood clotting. using fibrin from fibrinogen.
What are the two pathways of a clotting cascade?
Intrinsic pathway and extrinsic pathway
Function of thrombin
Form, fiber (fibrin)
Vitamin K dependent factors
•Factors:
2: prothrombin
7: serum, prothrombin conversion, •Excelerator
9: plasma, thromboplastin component
10: Stuart factor
•Dificient of factor :
8: hemophilia A
10: Stuart factor
What is tPA
Activate plasminogen
-Clot buster in clinical setting
*E.C *
ABO/Rh blood groups
Surface antigen
Definition of agglutination
Clumping of red blood cells
If the surface antigen is A what are the antibodies
Anti-B
If the surface antigen is AB, what is the antibodies?
No AB antibodies
Is the blood type dependent on surface antigen present?
True
What causes clumping?
Surface antigen, and antibodies
The surface antigen is AB, who can they receive from?
A, B, AB, O
If the surface antigen is O, who can it donate to?
A, B, AB,O
If the surface antigen is O, who can they receive from?
Only O
Does the blood mix between Mom and fetus?
No
Rh positive
Antigens are present on the surface of red blood cells
Rh negative
There are no antigens present on surface of red blood cells
Definition of crossmatch
Donor blood cells mix with recipients serum, vice versa
Complete red blood count
Number of red blood cells per microliter of blood
Why are females hemoglobin levels low
Because of menstruation and the female volume
What does it mean when there’s an elevated white blood cell count?
The body is fighting in infection, or an infection is present
What is antithrombin?
Produced by the liver, slowly inactivate thrombin