Ch 15 Flashcards
Lymphatic system
Collection of tissues and organs that bring populations of B cells and T cells into contact with antigens.
Lymphatic vessels
Flow within lymphatic system Happens here. Carry lymph.
Secondary lymphoid organs
Site where antigens that Have entered the body are brought into contact with dense populations of lymphocytes.
Antibody
Y shaped protein that binds antigen
Antigen
Molecule that reacts specifically with either an antibody or an antigen receptor on a lymphocyte
Cytotoxic T cells
Type of lymphocyte programmed to destroy infected or cancerous Self cells
Helper T cell
Type of lymphocyte programmed to activate B cells and macrophages. And assist other parts of the adaptive immune response.
Colonial selection
As lymphocytes mature in the primary lymphoid organ, population of cells able to recognize a variety of antigens is generated. Each cell however only responds to one epitope.
Immature lymphocytes
Not fully developed their antigen specific receptors
Naive lymphocytes
Have antigen receptors but have not yet encountered the antigen to which they are programmed to respond
Activated lymphocytes
Are able to proliferate. They recognize that a specific antigen is present because their antigen receptor has attached to it and they have received the second signal confirming that the antigen requires a response
Effector lymphocytes
These are descendants of activated lymphocytes, armed with the ability to produce specified cytokines or other protective substances. Plasma cells are examples.
Memory lymphocytes
Long lived descendants of activated lymphocytes. Can quickly become activated when antigen is encountered again. These are responsible for the speed and effectiveness of secondary response
Igm
First class produced during the primary response to an antigen. Principle class produced in responded to some t antigens. Activated complement system
Igg
Most abundant in blood and tissue fluids. Provides longest term protection of any antibody class. Transported across placenta into the fetus bloodstream.