Ch 11: Thyroid Hormone Action Flashcards
1
Q
What type of hormone is thyroid hormone?
A
a lipoprotein
2
Q
Which hormone travels to target cells on thyroxine binding globulin?
A
T4 (thyroxine)
3
Q
What does TBG do?
A
thyroxine-binding globulin carries T4 to target cells
4
Q
T3 is also known as
A
free iodine
5
Q
True/False: T3 is carried to target cells by TBG
A
FALSE - it is transported free of a carrier
6
Q
What happens to T4 in the target cell?
A
It gets converted to T3
7
Q
Where are receptor proteins located for thyroid family?
A
inside the nucleus, bound to DNA
8
Q
The hormone response element on the DNA has one half site for ___ and one half site for _____
A
T3; 9-cis-retinoic acid (a vitamin A derivative)
9
Q
T3 recruits ____ and removes ____
A
coactivators; corepressors
10
Q
Thyroid hormone action is similar to the action of….
A
Vitamin D
