Cephalosporins Flashcards
What are the 1st generation cephalosporins?
Cefazolin (Kefzol, Ancef), Cephalexin (Keflex)
Bugs not covered by cephalosporins
Listeria, Atypicals (Chlamyia, Mycoplasma), MRSA, Enterococci
What are the 2nd gen cephalosporins?
Cefoxitin (Mefoxin), cefaclor (Ceclor), cefuroxime (Ceftin)
Coverage of 1st gen cephs?
G(+) cocci, Proteus mirabilis, E. coli, Klebsiella pneumoniae (PEcK)
Coverage of 2nd gen cephs?
G(+) cocci, H. flu, Enterobacter aerogenes, Neisseria spp, Proteus mirabilis, E. coli, Klebsiella pneumoniae, Serratia marcescens (HEN PEcKS)
What are the 3rd gen cephs?
Ceftriaxone (Rocephin), cefotaxime (Claforan), ceftazidime
Coverage of 3rd gen cephs?
Serious G(-) infections resistant to other beta lactams
What specifically is ceftriaxone used to cover?
Meningitis and gonorrhea
What is ceftazidime specifically used to cover?
Pseudomonas
What is the 4th gen ceph?
Cefepime (Maxipime)
Coverage of 4th gen cephs?
Increased activity against Pseudmonas and G(+) organisms
What is the 5th gen ceph?
Ceftaroline (Teflaro)
Coverage of 5th gen cephs?
Broad G(+) and G- coverage including MRSA
What does 5th gen cephs not cover?
Pseudomonas
