Cephalosporins Flashcards
1
Q
Mechanism of Action
A
- Inhibit cell wall synthesis (like beta lactams)
- But are less resistant to degradation due to beta lactamases
2
Q
Route of Administration
A
- All are IV
- Exception: Keflex (Cephalexin)
3
Q
1st Generation
Faz and Flex
A
-Do not cross BBB
4
Q
2nd Generation
Tan Fox Fur
A
-Covers B. fragilis
5
Q
3rd Generation
Tri to Tax Taz
A
- Drug of choice for S. pneumoniae
- Works against P. aeruginosa
6
Q
4th Generation
A
-Works against P. aeruginosa (Cefepime)
7
Q
5th Generation
A
- Ceftaroline
- Only Cephalosporin that works against MRSA
8
Q
Keflex
A
- Cephalexin
- 1st Gen cephalosporin
- PO
- Does NOT cross BBB
9
Q
Teflaro
A
- Cefazolin
- 1st gen antibiotic
- Does not cross BBB
- IV
10
Q
Cefotetan
A
- 2nd gen cephalosporin
- Covers B. fragilis
11
Q
Cefoxitin
A
- 2nd gen cephalosporin
- Covers B. fragilis
12
Q
Cefuroxime
A
- 2nd gen cephalosporin
- Covers B. fragilis
13
Q
Ceftriaxone
A
- 3rd generation cephalosporin
- Eliminated though the bile
- Covers P. aeruginosa
- Can cross BBB
14
Q
Cefotaxime
A
- 3rd generation cephalosporin
- Drug of choice S. pneumoniae
- Usually with Avitbactam
