Cell Nucleus Flashcards
What are ribosomes?
Ribosomes carry out translation. The more protein synthesis a cell needs to do, the more ribosomes it has
What is the nucleus?
The nucleus contains most of the cells genes and genetic information. It is the cells control centre
What is the structure of the nucleus?
Surrounded by nuclear enveloped, has channels called nuclear pores, contains tightly packed DNA, prominent area called nucleolus
What is the nuclear envelope?
Composed of two membranes
Each membrane is a phospholipid bilayer
Outer membrane continuous with ER
What is nuclear lamina?
Inner surface of nuclear envelope
Composed of intermediate filaments (lamins)
Maintains shape of nucleus
Helps organise the packing of DNA
What are nuclear pores?
Channels made of proteins
Spans nuclear envelope
~1000 per cell
Controls movement of molecules out of or into nucleus
What moves from Nucleus to Cytoplasm?
mRNA, tRNA and ribosmal subunits move from nucleus to cytoplasm
- mRNA carrie’s information from a gene
- tRNA and ribosomal subunits are needed to build proteins
What moves from cytoplasm to nucleus?
Control signals, building materials and energy move from cytoplasm to nucleus
- Tells gene to turn on or off
- Building blocks of RNA
- Energy for chemical synthesis
What is the Nucleolus?
A prominent nuclear structure within non-dividing cells.
Non membrane bound specialised region within nucleus
Responsible for making rRNA and ribosomal subunits
How is DNA organised in the nucleus?
DNA helix interacts with histones forming a 10mm diameter fibre called a nucleoside. Further interactions cause another fibre to form. During cell division the fibres coil to form metaphase chromosomes
What is Euchromatin and Heterochromatin?
Euchromatin is less dense: contains genes being used by that cell
Heterochromatin is more dense: contains genes not being used
What is the relationship between euchromatin and heterochromatin?
Dynamic relationship
Transcription machinery needs to access specific DNA regions to begin transcription, euchromatin allows this