Cell Division

Question 1

Who is a cancer to Manchester United Football Club

Answer 1

Paul Pogba

Question 2

What are the hallmarks of cancer development?

Answer 2

1. Autonomy from growth signals
2. Evasion of growth inhibition
3. Unlimited replication
4. Invasion and metastases
5. Angiogenesis
6. Evasion of cell death

Question 3

What are the three main processes that cancer cell numbers are controlled?

Answer 3

1. Proliferation
2. Cell Death - apoptosis
3. Differentiation

Question 4

What are the three main classifications of carcinogens?

Answer 4

1. Radiation
2. Chemical
3. Infections

Question 5

What vaccination can protect against cervical cancer?

Answer 5

The human papilloma virus (HPV) vaccine

Question 6

What happens in the G0 Phase?

Answer 6

Resting Phase, where cells perform their preprogrammed roles or specialised function.

Question 7

What happens in the G1 Phase?

Answer 7

Interphase where the cell proteins and RNA are synthesised, including the proteins required for DNA synthesis

Question 8

What happens in the S Phase?

Answer 8

Synthesis of a second copy of DNA

Question 9

What happens in the G2 Phase?

Answer 9

DNA Synthesis stops but RNA and protein synthesis continues, also the mitotic spindles precursors are formed

Question 10

What happens in M Phase?

Answer 10

Mitosis! Cell divides after DNA segregation and produces a daughter cell

Question 11

What are phase specific drugs?

Answer 11

They have an effect only at a specific point in the cell cycle

Question 12

What are phase nonspecific drugs?

Answer 12

They have an effect anywhere in the cell cycle EXCEPT G0.

Question 13

What are cycle nonspecific drugs?

Answer 13

They have an effect at any point in the cell cycle INCLUDING G0