Cell Biology Flashcards

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1
Q

Explain the function of the following:
1) Cell membrane
2) Cytoplasm
3) Nucleus
4) Mitochondria

A

1) Cell membrane - holds the cell together and controls the movement of the substances in and out of the cell.

2) Cytoplasm - a fluid substance in the cell where most of the chemical reactions happen.

3) Nucleus - contains the genetic material that controls the activities of the cell.

4) Mitochondria - where most of the reactions for aerobic respiration takes place; respiration transfers energy that the cell needs to work.

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2
Q

Explain the function of the following:
1) Cell wall
2) Vacuole
3) Chloroplasts
4) Ribosomes

A

1) Cell wall - made of cellulose, which supports and strengthens the cell.

2) Vacuole - contains cell sap which provides structure and stores nutrients; weak solution of sugar and salts.

3) Chloroplasts - where photosynthesis occurs and provides food for the plant.

4) Ribosomes - where proteins are made in the cell.

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3
Q

Define Eukaryotic cells; give examples.
Define Prokaryotic cells; describe the structure and give an example.

A

1) Eukaryotic cells are organisms whose cells are organised into complex structures by internal membranes. Such as animal, plant and algal cells.

2) Prokaryotic cells are organisms without a cell nucleus or any other membrane bound organelles. These have a loop of DNA instead of a nucleus and most are uniceller, only some can be multicellar. Such as bacteria cells.

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4
Q

Describe the structure of a bacteria cell.

A
  • Cell membrane
  • Cell wall
  • Cytoplasm
  • May contain one or more small rings of DNA, Plasmids
  • Don’t have a true nucleus but a circular strand of DNA that floats freely in the cytoplasm.

No chloroplasts or mitochondria

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5
Q

Define magnification.
Define resolution.

A

Magnification enlarges an image to make the object appear bigger.
Resolution determines how clear and detailed the image is as it distinguishes between individual details.

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6
Q

State the formula for magnification.

A

Image size ÷ real size

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7
Q

What is the symbol for the following measurements and how to convert them?
* Centimetre
* Millimetre
* Micrometre
* Nanometre

A
  • Centimetre - cm (divide by 10)
  • Millimetre - mm (divide by 1000)
  • Micrometre - μm (divide by 1000)
  • Nanometre - nm
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8
Q

What should the observation drawing of what’s seen in the microscope include?

A
  • Drawing must take at least half the space with clear and unbroken lines.
  • When drawing cells, the sub-cellular structures should be in proportion
  • No colouring or shading
  • Must have a title and magnification
  • Label the important features using straight and uncorssed lines
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9
Q

What is the symbol for the following measurements and how to convert them?
* Milligrams
* Micrograms
* Nanograms
* Picograms

A
  • Milligrams - mg
  • Micrograms - μg
  • Nanograms - ng
  • Picograms - pg

To go down the list, multiply by 1000 each time.
To go up the list, divide by 1000 each time.

(DM)

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10
Q

How does Cell Differentiation and Specialisation occur?
1) Describe the process. When does it occur and what do cells develop?
2) Cells that differentiate in mature cells, what are they mainly used for? Give an example
3) What are undifferentiated cells called?

A

1) It’s a process in which a cell changes to become specialised for its job.
As cells change, they develop different sub-cellular structures and turn into different types of cells which allows them to carry out a specific function.
Most differentiation occurs as an organism develops.

2) Cells that differentiate in mature animals are mainly used for repairing and replacing cells, such as skin and blood cells.
3) Some cells are undifferentiated, that are called stem cells.

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11
Q

Specialised Cells

1) Describe the function of sperm cells.
2) State the characteristics and give a reason for it. (3)

A

1) Specialised for reproduction to get the male DNA to the female DNA.

2) Characteristics:
* long tail and streamlined head to help swim to egg
* lots of mitochondria to provide the energy needed
* carries enzymes in its head to digest through the egg cell membrane

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12
Q

Specialised Cells

1) Describe the function of nerve cells.
2) State the characteristics and give a reason. (2)

A

1) Specialised for rapid signalling; to carry electrical signals from one part of body to another.

2) Characteristics:
* they are long so they can cover more distance
* branched connections at their ends to connect to other nerve cells and form a network throughout the body.

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13
Q

Specialised Cells

1) Describe the function of muscle cells.
2) State the characteristics and give a reason. (2)

A

1) Specialised for contraction; to contract quickly.

2) Characteristics:
* they are long so they have space to contract
* contains lots of mitochondria to generate the energy needed.

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14
Q

Specialised Cells

1) Describe the function of root hair cells.
2) State the characteristics and give a reason. (1)

A

1) Specialised for absorbing water and minerals, on the surface of plant roots.

2) Characteristic:
* grows into long hairs to stick out into the soil which gives plants bigger surface area to absorb nutrients from soil.

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15
Q

Specialised Cells

1) Describe the function of phloem and xylem cells.
2) State the characteristics and give a reason. (3) there’s one for phloem and one for xylem.

A

1) Specialised for transporting substances (food and water) around the plant through the phloem and xylem tubes.

2) Characteristics:
* the cells are long that join from end to end to form the tubes
* xylem cells are hollow in centre
* phloem cells have very few sub-cellular structures so that nutrients can flow through them.

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16
Q

Define the following:
* Gene
* Chromosome
* DNA

A
  • Gene - a section of DNA that codes for a specific characteristics.
  • Chromosome - coiled up lengths of DNA molecules.
  • DNA - the genetic information that determines the characteristics, a double helix strand of DNA.
17
Q

Put the following from smallest to biggest:
* Chromosomes
* Genes
* Cell
* Nucleus
* DNA

A

Smallest
Genes
DNA
Chromosomes
Nucleus
Cell
Biggest

18
Q

Which organims use mitosis to grow and replace cells that are damaged?
What happens at the end of the cell cycle?

A

Multicellular organisms.

At the end of the cell cycle, two new identical cells are produced to the original cell with **same number **of chromosomes.

19
Q

What does the cell has to do before dividing?
What happens to the chromosomes?
What does the DNA form?

A

1) Before the cell divides, the cell has to grow and increase the amount of sub-cellular structures like mitochondria.

2) it then duplicates the DNA, the 46 chromosomes are copied to make 92 chromosomes.

3) The 92 chromosomes are then shared between two daughter cells.

4) The DNA forms a X-shaped chromosome.

20
Q

Define mitosis.

A

The process of cell division, the cell divides into two identical daughter cells.

21
Q

Describe the process of Mitosis.
What happens to the chromosomes in the cell?
What becomes the nuclei of the new cells?
Which sub-cellular structures divide?

A

1) Chromosomes line up at the centre of the nucleus and cell fibres pull them apart. The two arms of each chromosomes go to the opposite end of the cell.

2) Membranes form around each set of chromosomes that become the nuclei of the two new cells; the nucleus has divided.

3) Cytoplams and cell membrane divide.

4) The cell has now produced two new daughter cells.

22
Q

Define stem cells.
Define embryo
1) How can stem cells divide?

A

These are able to produce many cells of the same type that can grow into any type of cell by cell differentiation; not specialised cell yet.

Embryo are small group of cells.

1) By mitosis

23
Q

1) Where are stem cells found?
2) What are stem cells called in the early stages of development?
3) Why do doctors like them?
4) Embryonic stem cells can’t turn into any type of cell; which cells are exception to this?

A

1) Stem cells are found in early human embryos.

2) Embryonic cells

3) Because they have the potential to turn into any type of cell.

4) Blood cells

24
Q

1) Stem cells from embryonic and bone marrow can be grown in lab to do what?
2) Which type of cells can adult stem cells differentiate into? What can’t they form?

A

1) They are grown to produce clones (genetically identical cells) and can be made to differentiate into specialised cells to use in medicine or research.

2) Adult stem cells can only differentiate into blood cells like red blood cells, white blood cells and platelets. They can’t form tissues like embryonic stem cells.

25
Q

What is embryonic cells used for? give an example.

What is therapeutic cloning? Why can’t the patient’s body reject the stem cells produced by this process?

A

Embryonic stem cells is used to replace faulty cells in sick people such as making insulin-producing cells for people with diabetes or nerve cells for people paralysed by spinal injuries.

Therapeutic cloning is when an embryo is made to have same genetic information as the patient, meaning stem cells produced from it with have same genes so it wouldn’t be rejected if replaced by faulty genes.

26
Q

1) Why are embryonic cells more useful than adult cells? What is the more scientific name for this?
2) What are risks for using stem cells in treatment?

A

1) Because they can grow into more different types of cells; umbilical cord blood cells.
2) Stem cells that are grown into the lab, can be contaminated with a virus that could be passed onto the patient and make their condition even worse.

27
Q

Disadvantages of using the following stem cell methods:
* Embryonic stem cells
* Adult stem cells

Why can’t adult stem cells cause rejection?

A

Embryonic stem cells:
* requires embryonic stem cells that have limited supply as they only come from embryos. There are also some ethical issues.
* patient’s immune system may reject the stem cells due to different genomes. It tries to destroy them as they don’t recognise them.
This can be prevented by giving the patient medications to supress their immune system; but doesn’t always work and has side effects.

Adult stem cells:
* they can only differentiate into blood cells and can only treat blood related diseases.

They can’t cause rejection because they are taken from the patient’s bone marrow.

28
Q

What are the two risks of using stem cells in medicine?
What are the ethical issues with stem cells?
What the laws of using stem cells in countries?

A

1) Virus transmission - if the stem cells are infected with a virus either before taken by scientists or in the lab, the virus is also transferred to the patient.

2) Tumor development - as stem cells can divide rapidly, they can get out of control once they have been transplanted into the patient that can develop into tutor or cancer.

3) Some countires have banned the stem cells research that use embryos. In UK it’s legal, but scientists have to follow strict rules.

29
Q

Why don’t the embryos used for research have a potential for human life?

A

Some people object to this as they believe that they have a potential for a human life. On the other hand, some people think it’s more important to treat the unwell people than the rights of embryos.

However, the embryos are usually the unwanted ones from fertility clinics that would have been destroyed otherwise as they wouldn’t have developed into a human anyway.

30
Q

How does alveoli carry out the gas exchange in the body?
Explain the process.

A

The blood passing next to the alveoli has returned TO the lungs, from the rest of the body which means it contains more CO2 and less oxygen.

  • Oxygen diffuses out of the alveoli (where there’s high concentration) and into the blood (where there’s low concentration).
  • CO2 diffuses out the blood and into the alveoli as there’s less CO2 concentration in the alveoli so it can be breathed out.
  • When the blood reaches body cells, oxygen is released from red blood cells and diffuses into the body cells due to low concentration in the body cells of the oxygen.
  • At the same time, CO2 diffuses out of body cells and into the blood where there’s low concentration, for it to be carried back to the lungs.
31
Q

Name 3 features of the alveoli that helps with gas exchange. (5)

A
  • Large surface area; allows more space for the gas exchange of oxygen and carbon dioxide.
  • Very thin walls; provides a short diffusion pathway for the gas exchange
  • Moist lining; allowing gases to dissolve which allows them to diffuse across the lining
  • Good blood supply; allows gas exchange to happen at a faster rate.
  • Good ventilation; provides good supply of air. (only state this one if you can’t remember the other 4 above)
32
Q

How does active transport stop us from starving?

A

It’s used in the gut when there’s low conc of nutrient in the gut and high conc in the blood.
* When there’s high conc of glucose and amino acids in the gut, they naturally diffuse into the blood
* But sometimes its the opposite, meaning it’s against the concentration gradient and active transport take place.
* It allows glucose to be taken into the blood when the blood is aready higher than the gut and then transported to cells.

33
Q

Where is the villi?
How is the villi adapted for substance exchange?

A

The inside of the small intestine is covered in millions of tiny villi.
* They increase the surface area so digested food is absorbed more quickly into the blood
* They are a single layer of surface cells
* A very good supply to assist quick absorption.
* Network of capillaries

34
Q

What are gills?
How are they adapted for gas exchange?

A

They are the gas exchange surfaces in the fish.

  • Each is made up of lots of thin plates, gill filaments, giving a big surface area for gas exchange
  • Gill filaments are covered in many tiny lamellae increasing surface area even more
  • The lamellae has lots of capillaries to speed of difussion
  • Thin surface layers of cells to minimise distance of gas exchange
35
Q

Describe the concentration gradients of different substances in the gill.

A

Blood flows through lamellae in one direction
Water flows in the opposite direction, meaning a large conc gradient between water and blood.

Conc of oxygen in water is always high than in blood, so oxygen diffuses into the blood.