Cefalosporinas Flashcards

1
Q

macanismo de accion

A

bactericida. inhibe sintesis de la pared. Categoria B.

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2
Q

Generaciones

A

5

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3
Q

Tratamiento de elccion en meingitis

A

Ceftriaxona + vanco OJO ampi en emb vanco para cubrir coco gram + multiresistente como el neumococo ya que si el neumococo es resistente a la ceftriaxona debe ser sensible a la vancomicina.
Ahora si es una paciente embarazada le agrego ampicilina porque debo cubrir listeria ya que el 15% de la meningitis en embarazada son causados por listeria

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4
Q

agentes ma frecuentes de meningitis

A

Neumococo
N. meningitidis
H. influenzae

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5
Q

CF de 1ra (las 4 cefa) Cobertura.

A

Cefalexina VO, cefadroxilo VO, cefazolina EV, cefalotina EV

Cubren CG+ (solo staph y strep) y BG-

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6
Q

Diferencia entre cefazolina y cefalotina si ambas son 1ra generacion y se dan EV

A

cefazolina es cada 8h y cefalotina cada 6h

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7
Q

2da generacion (3) y cobertura

A

1) Cefoxitin EV
2) Cefuroxima VO
3) Cefaclor VO
Cubren CG+, CG-. BG- y anaerobios

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8
Q

CF de 2da que se puede usar para NAC

A

Cefuroxima en dado caso de no tener amoxi+clavulanato (Nelson)

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9
Q

Uso del cefaclor (CF de 2da)

A

Sinusitis, OMA, IPTB, se usa solo para infecciones de vias resp altas NO neumonia

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10
Q

CF de 3era (6) y cobertura

A

!) cefatazidima y cefoperazona (EV)

2) ceftrixona (EV, IM) y cefotaxima (EV)
3) Cfepodoxima y cefixima VO

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11
Q

CF 4ta

A

Cefepime y cefpirome

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12
Q

CF 5ta

A

Ceftarolina y ceftobiprole

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13
Q

Cubren pseudomona

A

Ceftazidima, cefoperazona, cefepime y ceftobiprole

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